DYNAMICS OF CD14+СD16+ MONOCYTE SUBPOPULATIONS IN COMPLICATION-FREE SYSTEMIC INFLAMMATORY RESPONSE FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY

Abstract. Time dynamics of CD14 and СD16 antigen expression on the surface of peripheral blood monocytes and serum cytokine contents was evaluated at different terms after surgical intervention in patients undergoing on-pump coronary artery bypass graft surgery. An association has been shown between...

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Autores principales:	V. G. Matveeva, A. S. Golovkin, I. V. Kudryavtsev, E. V. Grigoriev, M. N. Chernova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	monocytes cd14+cd16+ subsets cabg surgery systemic inflammatory response Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/667254c4dd2544448b41ea958ea55196
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spelling	oai:doaj.org-article:667254c4dd2544448b41ea958ea551962021-11-18T08:03:41ZDYNAMICS OF CD14+СD16+ MONOCYTE SUBPOPULATIONS IN COMPLICATION-FREE SYSTEMIC INFLAMMATORY RESPONSE FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY1563-06252313-741X10.15789/1563-0625-2012-4-5-391-398https://doaj.org/article/667254c4dd2544448b41ea958ea551962014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/473https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Time dynamics of CD14 and СD16 antigen expression on the surface of peripheral blood monocytes and serum cytokine contents was evaluated at different terms after surgical intervention in patients undergoing on-pump coronary artery bypass graft surgery. An association has been shown between severity of organ dysfunctions, as assessed by SOFA scores, and concentrations of IL-6 and IL-10 during early postoperative terms. On day +1 after surgery, the monocyte subpopulation profile was changed, due to relative decrease in CD14hiCD16– and increase in CD14hiCD16+. Expression of CD14 on the surface of CD14hiCD16–is reduced, along with increased expression of CD16 receptor. The observed association between relative CD14hiCD16– contents, CD16 expression level on CD14hiCD16+ monocyte subpopulation, and SOFA scores suggest a significant contribution of above-mentioned subpopulations to clinical course at early terms after surgical intervention.V. G. MatveevaA. S. GolovkinI. V. KudryavtsevE. V. GrigorievM. N. ChernovaSPb RAACIarticlemonocytescd14+cd16+ subsetscabg surgerysystemic inflammatory responseImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 14, Iss 4-5, Pp 391-398 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	monocytes cd14+cd16+ subsets cabg surgery systemic inflammatory response Immunologic diseases. Allergy RC581-607
spellingShingle	monocytes cd14+cd16+ subsets cabg surgery systemic inflammatory response Immunologic diseases. Allergy RC581-607 V. G. Matveeva A. S. Golovkin I. V. Kudryavtsev E. V. Grigoriev M. N. Chernova DYNAMICS OF CD14+СD16+ MONOCYTE SUBPOPULATIONS IN COMPLICATION-FREE SYSTEMIC INFLAMMATORY RESPONSE FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY
description	Abstract. Time dynamics of CD14 and СD16 antigen expression on the surface of peripheral blood monocytes and serum cytokine contents was evaluated at different terms after surgical intervention in patients undergoing on-pump coronary artery bypass graft surgery. An association has been shown between severity of organ dysfunctions, as assessed by SOFA scores, and concentrations of IL-6 and IL-10 during early postoperative terms. On day +1 after surgery, the monocyte subpopulation profile was changed, due to relative decrease in CD14hiCD16– and increase in CD14hiCD16+. Expression of CD14 on the surface of CD14hiCD16–is reduced, along with increased expression of CD16 receptor. The observed association between relative CD14hiCD16– contents, CD16 expression level on CD14hiCD16+ monocyte subpopulation, and SOFA scores suggest a significant contribution of above-mentioned subpopulations to clinical course at early terms after surgical intervention.
format	article
author	V. G. Matveeva A. S. Golovkin I. V. Kudryavtsev E. V. Grigoriev M. N. Chernova
author_facet	V. G. Matveeva A. S. Golovkin I. V. Kudryavtsev E. V. Grigoriev M. N. Chernova
author_sort	V. G. Matveeva
title	DYNAMICS OF CD14+СD16+ MONOCYTE SUBPOPULATIONS IN COMPLICATION-FREE SYSTEMIC INFLAMMATORY RESPONSE FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY
title_short	DYNAMICS OF CD14+СD16+ MONOCYTE SUBPOPULATIONS IN COMPLICATION-FREE SYSTEMIC INFLAMMATORY RESPONSE FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY
title_full	DYNAMICS OF CD14+СD16+ MONOCYTE SUBPOPULATIONS IN COMPLICATION-FREE SYSTEMIC INFLAMMATORY RESPONSE FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY
title_fullStr	DYNAMICS OF CD14+СD16+ MONOCYTE SUBPOPULATIONS IN COMPLICATION-FREE SYSTEMIC INFLAMMATORY RESPONSE FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY
title_full_unstemmed	DYNAMICS OF CD14+СD16+ MONOCYTE SUBPOPULATIONS IN COMPLICATION-FREE SYSTEMIC INFLAMMATORY RESPONSE FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY
title_sort	dynamics of cd14+сd16+ monocyte subpopulations in complication-free systemic inflammatory response following coronary artery bypass graft surgery
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/667254c4dd2544448b41ea958ea55196
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_version_	1718422481201528832

DYNAMICS OF CD14+СD16+ MONOCYTE SUBPOPULATIONS IN COMPLICATION-FREE SYSTEMIC INFLAMMATORY RESPONSE FOLLOWING CORONARY ARTERY BYPASS GRAFT SURGERY

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