A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates

A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates

Summary: Activation of nucleic acid sensing Toll-like receptors (TLRs) in B cells is involved in antiviral responses by promoting B cell activation and germinal center responses. In order to take advantage of this natural pathway for vaccine development, synthetic pathogen-like antigens (PLAs) const...

Full description

Saved in:
Bibliographic Details
Main Authors: Chang Guo, Yanan Peng, Lin Lin, Xiaoyan Pan, Mengqi Fang, Yun Zhao, Keyan Bao, Runhan Li, Jianbao Han, Jiaorong Chen, Tian-Zhang Song, Xiao-Li Feng, Yahong Zhou, Gan Zhao, Leike Zhang, Yongtang Zheng, Ping Zhu, Haiying Hang, Linqi Zhang, Zhaolin Hua, Hongyu Deng, Baidong Hou
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
COVID-19
SARS-CoV-2
RBD
vaccine
B cells
Toll-like receptor
Medicine (General)
R5-920
Online Access:https://doaj.org/article/6677d99468274bcea69009e391b42d59
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/6677d99468274bcea69009e391b42d59

Similar Items