Zn2+-dependent DNAzymes that cleave all combinations of ribonucleotides

Inomata et al. isolate zinc-dependent DNAzymes with compact catalytic core sequences displaying highly versatile hydrolysis activity. The cleavable substrate variation for the DNAzymes (ZincDz2 and ZincDz2-v2) is very broad and the authors further demonstrate their utility by showing ZincDz2 can hyd...

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Autores principales: Rika Inomata, Jing Zhao, Makoto Miyagishi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/667af51242b84672bb30a21379eb5f19
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