Activity-Related Conformational Changes in <sc>d,d</sc>-Carboxypeptidases Revealed by <italic toggle="yes">In Vivo</italic> Periplasmic Förster Resonance Energy Transfer Assay in <italic toggle="yes">Escherichia coli</italic>

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Activity-Related Conformational Changes in <sc>d,d</sc>-Carboxypeptidases Revealed by <italic toggle="yes">In Vivo</italic> Periplasmic Förster Resonance Energy Transfer Assay in <italic toggle="yes">Escherichia coli</italic>

ABSTRACT One of the mechanisms of β-lactam antibiotic resistance requires the activity of d,d-carboxypeptidases (d,d-CPases) involved in peptidoglycan (PG) synthesis, making them putative targets for new antibiotic development. The activity of PG-synthesizing enzymes is often correlated with their a...

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Autores principales:	Nils Y. Meiresonne, René van der Ploeg, Mark A. Hink, Tanneke den Blaauwen
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2017
Materias:	FRET PBP5 PBP6a PBP6b antibiotics mCherry Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/667f6b6d758e4d2bb1bbb84ac97a7682
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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