Differential Alphavirus Defective RNA Diversity between Intracellular and Extracellular Compartments Is Driven by Subgenomic Recombination Events
ABSTRACT Alphaviruses are positive-sense RNA arboviruses that can cause either a chronic arthritis or a potentially lethal encephalitis. Like other RNA viruses, alphaviruses produce truncated, defective viral RNAs featuring large deletions during replication. These defective RNAs (D-RNAs) have prima...
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Autores principales: | R. M. Langsjoen, A. E. Muruato, S. R. Kunkel, E. Jaworski, A. Routh |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/66953552e03e4ec99e26bd61934a4b68 |
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