Differential Alphavirus Defective RNA Diversity between Intracellular and Extracellular Compartments Is Driven by Subgenomic Recombination Events

ABSTRACT Alphaviruses are positive-sense RNA arboviruses that can cause either a chronic arthritis or a potentially lethal encephalitis. Like other RNA viruses, alphaviruses produce truncated, defective viral RNAs featuring large deletions during replication. These defective RNAs (D-RNAs) have prima...

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Bibliographic Details
Main Authors: R. M. Langsjoen, A. E. Muruato, S. R. Kunkel, E. Jaworski, A. Routh
Format: article
Language:EN
Published: American Society for Microbiology 2020
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Online Access:https://doaj.org/article/66953552e03e4ec99e26bd61934a4b68
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