Possible association between periodontitis and prostatitis: A pilot study

Introduction: Prostatitis is one of the most chronic diseases which is often associated with periodontitis. The serum Prostate Specific Antigen (PSA) levels can be elevated in a non-malignant condition such as symptomatic and asymptomatic prostatitis. Similarity in the inflammatory etiopathogenesis...

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Autores principales:	Stefanovska Emilija S., Zabokova-Bilbilova Efka N., Peshevska Snežana J., Ristoska Stevica M., Mindova Sonja J., Dohcev Sasho K., Panovska-Petrusheva Aleksandra V.
Formato:	article
Lenguaje:	EN SR
Publicado:	Medicinski fakultet i Klinika za stomatologiju, Niš 2021
Materias:	periodontitis prostate specific antigen prostatitis Dentistry RK1-715
Acceso en línea:	https://doaj.org/article/669b48db02064df9874003f81658f866
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spelling	oai:doaj.org-article:669b48db02064df9874003f81658f8662021-12-05T18:00:43ZPossible association between periodontitis and prostatitis: A pilot study0352-52521820-120210.5937/asn2183146Shttps://doaj.org/article/669b48db02064df9874003f81658f8662021-01-01T00:00:00Zhttps://scindeks-clanci.ceon.rs/data/pdf/0352-5252/2021/0352-52522183146S.pdfhttps://doaj.org/toc/0352-5252https://doaj.org/toc/1820-1202Introduction: Prostatitis is one of the most chronic diseases which is often associated with periodontitis. The serum Prostate Specific Antigen (PSA) levels can be elevated in a non-malignant condition such as symptomatic and asymptomatic prostatitis. Similarity in the inflammatory etiopathogenesis of these diseases is evident through the presence of Gram negative bacteremia, which in turn may be the possible link between these two conditions. Aim: To estimate the possible association between chronic periodontitis and prostatitis, evaluating the PSA levels in patients with moderate and severe periodontitis. Material and methods: 40 patients with prostatitis and elevated Prostate Specific Antigen (PSA) levels (≥ 4ng/ml) that participated in the study were hospitalized at the University Urology Clinic at the Faculty of Medicine in Skopje. Patients were divided into two groups on the basis of the levels of periodontal clinical attachment. First group of 20 patients with Clinical attachment level (CAL) ≥ 3mm, moderate periodontitis and other group of 20 patients with CAL ≥ 5mm, severe periodontitis. Dental plaque index (DPI), Index of gingival inflammation (IGI), Gingival bleeding index (GBI) and Clinical attachment level (CAL) were recorded and an assessment of PSA values was done and correlation to periodontal parameters, respectively. Differences in means, as statistically significant, were analyzed using Student's ttest. The relationship between PSA scores with all clinical parameters was done using Pearson's correlation coefficient technique. Results: Statistically significant differences were noted, (p<0.05) between periodontal index values (DPI, IGI, GBI, CAL) and PSA levels within the two examined groupsHigher PSA levels were recordedin patients with severe periodontitis than inthose with moderate periodontitis. Pearson coefficient test among these periodontal indices (DPI, IGI, GBI and CAL) and PSA levels in two examined groups showed no statistically significant correlation. Conclusion: Patients with severe periodontitis were found to have higher PSA levels than those with moderate periodontitis. The clinical parameters of periodontitis and elevated PSA levels indicated a probable link between the two diseases.Stefanovska Emilija S.Zabokova-Bilbilova Efka N.Peshevska Snežana J.Ristoska Stevica M.Mindova Sonja J.Dohcev Sasho K.Panovska-Petrusheva Aleksandra V.Medicinski fakultet i Klinika za stomatologiju, Nišarticleperiodontitisprostate specific antigenprostatitisDentistryRK1-715ENSRActa Stomatologica Naissi, Vol 37, Iss 83, Pp 2146-2157 (2021)
institution	DOAJ
collection	DOAJ
language	EN SR
topic	periodontitis prostate specific antigen prostatitis Dentistry RK1-715
spellingShingle	periodontitis prostate specific antigen prostatitis Dentistry RK1-715 Stefanovska Emilija S. Zabokova-Bilbilova Efka N. Peshevska Snežana J. Ristoska Stevica M. Mindova Sonja J. Dohcev Sasho K. Panovska-Petrusheva Aleksandra V. Possible association between periodontitis and prostatitis: A pilot study
description	Introduction: Prostatitis is one of the most chronic diseases which is often associated with periodontitis. The serum Prostate Specific Antigen (PSA) levels can be elevated in a non-malignant condition such as symptomatic and asymptomatic prostatitis. Similarity in the inflammatory etiopathogenesis of these diseases is evident through the presence of Gram negative bacteremia, which in turn may be the possible link between these two conditions. Aim: To estimate the possible association between chronic periodontitis and prostatitis, evaluating the PSA levels in patients with moderate and severe periodontitis. Material and methods: 40 patients with prostatitis and elevated Prostate Specific Antigen (PSA) levels (≥ 4ng/ml) that participated in the study were hospitalized at the University Urology Clinic at the Faculty of Medicine in Skopje. Patients were divided into two groups on the basis of the levels of periodontal clinical attachment. First group of 20 patients with Clinical attachment level (CAL) ≥ 3mm, moderate periodontitis and other group of 20 patients with CAL ≥ 5mm, severe periodontitis. Dental plaque index (DPI), Index of gingival inflammation (IGI), Gingival bleeding index (GBI) and Clinical attachment level (CAL) were recorded and an assessment of PSA values was done and correlation to periodontal parameters, respectively. Differences in means, as statistically significant, were analyzed using Student's ttest. The relationship between PSA scores with all clinical parameters was done using Pearson's correlation coefficient technique. Results: Statistically significant differences were noted, (p<0.05) between periodontal index values (DPI, IGI, GBI, CAL) and PSA levels within the two examined groupsHigher PSA levels were recordedin patients with severe periodontitis than inthose with moderate periodontitis. Pearson coefficient test among these periodontal indices (DPI, IGI, GBI and CAL) and PSA levels in two examined groups showed no statistically significant correlation. Conclusion: Patients with severe periodontitis were found to have higher PSA levels than those with moderate periodontitis. The clinical parameters of periodontitis and elevated PSA levels indicated a probable link between the two diseases.
format	article
author	Stefanovska Emilija S. Zabokova-Bilbilova Efka N. Peshevska Snežana J. Ristoska Stevica M. Mindova Sonja J. Dohcev Sasho K. Panovska-Petrusheva Aleksandra V.
author_facet	Stefanovska Emilija S. Zabokova-Bilbilova Efka N. Peshevska Snežana J. Ristoska Stevica M. Mindova Sonja J. Dohcev Sasho K. Panovska-Petrusheva Aleksandra V.
author_sort	Stefanovska Emilija S.
title	Possible association between periodontitis and prostatitis: A pilot study
title_short	Possible association between periodontitis and prostatitis: A pilot study
title_full	Possible association between periodontitis and prostatitis: A pilot study
title_fullStr	Possible association between periodontitis and prostatitis: A pilot study
title_full_unstemmed	Possible association between periodontitis and prostatitis: A pilot study
title_sort	possible association between periodontitis and prostatitis: a pilot study
publisher	Medicinski fakultet i Klinika za stomatologiju, Niš
publishDate	2021
url	https://doaj.org/article/669b48db02064df9874003f81658f866
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Possible association between periodontitis and prostatitis: A pilot study

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