Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling

Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.

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Auteurs principaux: Melinda Liu Perkins, Dirk Benzinger, Murat Arcak, Mustafa Khammash
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/66a0e8a410b8447d89243a33e77da954
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Résumé:Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.