Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.
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Nature Portfolio
2020
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oai:doaj.org-article:66a0e8a410b8447d89243a33e77da9542021-12-02T15:33:50ZCell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling10.1038/s41467-020-15166-32041-1723https://doaj.org/article/66a0e8a410b8447d89243a33e77da9542020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15166-3https://doaj.org/toc/2041-1723Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.Melinda Liu PerkinsDirk BenzingerMurat ArcakMustafa KhammashNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
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Science Q Melinda Liu Perkins Dirk Benzinger Murat Arcak Mustafa Khammash Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling |
description |
Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling. |
format |
article |
author |
Melinda Liu Perkins Dirk Benzinger Murat Arcak Mustafa Khammash |
author_facet |
Melinda Liu Perkins Dirk Benzinger Murat Arcak Mustafa Khammash |
author_sort |
Melinda Liu Perkins |
title |
Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling |
title_short |
Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling |
title_full |
Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling |
title_fullStr |
Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling |
title_full_unstemmed |
Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling |
title_sort |
cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/66a0e8a410b8447d89243a33e77da954 |
work_keys_str_mv |
AT melindaliuperkins cellinthelooppatternformationwithoptogeneticallyemulatedcelltocellsignaling AT dirkbenzinger cellinthelooppatternformationwithoptogeneticallyemulatedcelltocellsignaling AT muratarcak cellinthelooppatternformationwithoptogeneticallyemulatedcelltocellsignaling AT mustafakhammash cellinthelooppatternformationwithoptogeneticallyemulatedcelltocellsignaling |
_version_ |
1718386964811481088 |