Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling

Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.

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Autores principales: Melinda Liu Perkins, Dirk Benzinger, Murat Arcak, Mustafa Khammash
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/66a0e8a410b8447d89243a33e77da954
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spelling oai:doaj.org-article:66a0e8a410b8447d89243a33e77da9542021-12-02T15:33:50ZCell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling10.1038/s41467-020-15166-32041-1723https://doaj.org/article/66a0e8a410b8447d89243a33e77da9542020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15166-3https://doaj.org/toc/2041-1723Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.Melinda Liu PerkinsDirk BenzingerMurat ArcakMustafa KhammashNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Melinda Liu Perkins
Dirk Benzinger
Murat Arcak
Mustafa Khammash
Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
description Synthetic biological pattern formation is challenging to engineer due to theoretical complexity and practical limitations. Here, the authors introduce a cell-in-the-loop approach in which cells interact through in silico signaling.
format article
author Melinda Liu Perkins
Dirk Benzinger
Murat Arcak
Mustafa Khammash
author_facet Melinda Liu Perkins
Dirk Benzinger
Murat Arcak
Mustafa Khammash
author_sort Melinda Liu Perkins
title Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
title_short Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
title_full Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
title_fullStr Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
title_full_unstemmed Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
title_sort cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/66a0e8a410b8447d89243a33e77da954
work_keys_str_mv AT melindaliuperkins cellinthelooppatternformationwithoptogeneticallyemulatedcelltocellsignaling
AT dirkbenzinger cellinthelooppatternformationwithoptogeneticallyemulatedcelltocellsignaling
AT muratarcak cellinthelooppatternformationwithoptogeneticallyemulatedcelltocellsignaling
AT mustafakhammash cellinthelooppatternformationwithoptogeneticallyemulatedcelltocellsignaling
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