Corticosteroid response in children with nephrotic syndrome, Amirkola Children Hospital, 1994-2001

Background and Objective: Nephrotic syndrome (NS) is one of the kidney diseases in children that was with high mortality and morbidity before starting of management with corticosteroid (CS). Of course, some patients are resistant to CS and do not respond to CS. This study was done to evaluate the re...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	H Sorkhi, E Alavi, A Bijani
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2002
Materias:	children nephrotic syndrome corticosteroid Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/66a3b8dc8138466c9d7453f19046e9ee
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:66a3b8dc8138466c9d7453f19046e9ee
record_format	dspace
spelling	oai:doaj.org-article:66a3b8dc8138466c9d7453f19046e9ee2021-11-10T09:19:40ZCorticosteroid response in children with nephrotic syndrome, Amirkola Children Hospital, 1994-20011561-41072251-7170https://doaj.org/article/66a3b8dc8138466c9d7453f19046e9ee2002-07-01T00:00:00Zhttp://jbums.org/article-1-2821-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: Nephrotic syndrome (NS) is one of the kidney diseases in children that was with high mortality and morbidity before starting of management with corticosteroid (CS). Of course, some patients are resistant to CS and do not respond to CS. This study was done to evaluate the resistance and responsiveness to CS. Methods: This analytical study was done on all patients with NS disease who admitted in Amirkola children hospital during 1994-2001. These patients were treated with 60 mg/m² of prednisolone for 4 weeks and then response to CS was evaluated. Findings: Among 73 patients, the ratio of female to male was 1.6 to 1 and most of patients were at the 2-8 age group and were involved in winter (P=0.012). 74% of patients responded to CS, but 26% were resistant to CS. The most responsiveness to CS was at the 2-8 age group (89%). There was not a difference between females and males for response to CS. Conclusion: In this study, response to CS in children with NS was the same with those in some areas and different to others but like other studies, children at the 2-8 age group were involved. Therefore, it is recommended that every patient in this age can be treated with CS without using other invasive diagnostic procedure.H SorkhiE AlaviA BijaniBabol University of Medical Sciencesarticlechildrennephrotic syndromecorticosteroidMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 4, Iss 3, Pp 39-43 (2002)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	children nephrotic syndrome corticosteroid Medicine R Medicine (General) R5-920
spellingShingle	children nephrotic syndrome corticosteroid Medicine R Medicine (General) R5-920 H Sorkhi E Alavi A Bijani Corticosteroid response in children with nephrotic syndrome, Amirkola Children Hospital, 1994-2001
description	Background and Objective: Nephrotic syndrome (NS) is one of the kidney diseases in children that was with high mortality and morbidity before starting of management with corticosteroid (CS). Of course, some patients are resistant to CS and do not respond to CS. This study was done to evaluate the resistance and responsiveness to CS. Methods: This analytical study was done on all patients with NS disease who admitted in Amirkola children hospital during 1994-2001. These patients were treated with 60 mg/m² of prednisolone for 4 weeks and then response to CS was evaluated. Findings: Among 73 patients, the ratio of female to male was 1.6 to 1 and most of patients were at the 2-8 age group and were involved in winter (P=0.012). 74% of patients responded to CS, but 26% were resistant to CS. The most responsiveness to CS was at the 2-8 age group (89%). There was not a difference between females and males for response to CS. Conclusion: In this study, response to CS in children with NS was the same with those in some areas and different to others but like other studies, children at the 2-8 age group were involved. Therefore, it is recommended that every patient in this age can be treated with CS without using other invasive diagnostic procedure.
format	article
author	H Sorkhi E Alavi A Bijani
author_facet	H Sorkhi E Alavi A Bijani
author_sort	H Sorkhi
title	Corticosteroid response in children with nephrotic syndrome, Amirkola Children Hospital, 1994-2001
title_short	Corticosteroid response in children with nephrotic syndrome, Amirkola Children Hospital, 1994-2001
title_full	Corticosteroid response in children with nephrotic syndrome, Amirkola Children Hospital, 1994-2001
title_fullStr	Corticosteroid response in children with nephrotic syndrome, Amirkola Children Hospital, 1994-2001
title_full_unstemmed	Corticosteroid response in children with nephrotic syndrome, Amirkola Children Hospital, 1994-2001
title_sort	corticosteroid response in children with nephrotic syndrome, amirkola children hospital, 1994-2001
publisher	Babol University of Medical Sciences
publishDate	2002
url	https://doaj.org/article/66a3b8dc8138466c9d7453f19046e9ee
work_keys_str_mv	AT hsorkhi corticosteroidresponseinchildrenwithnephroticsyndromeamirkolachildrenhospital19942001 AT ealavi corticosteroidresponseinchildrenwithnephroticsyndromeamirkolachildrenhospital19942001 AT abijani corticosteroidresponseinchildrenwithnephroticsyndromeamirkolachildrenhospital19942001
_version_	1718440106782621696

Corticosteroid response in children with nephrotic syndrome, Amirkola Children Hospital, 1994-2001

Ejemplares similares