Xanthurenic acid binds to neuronal G-protein-coupled receptors that secondarily activate cationic channels in the cell line NCB-20.

Xanthurenic acid (XA) is a metabolite of the tryptophan oxidation pathway through kynurenine and 3-hydroxykynurenine. XA was until now considered as a detoxification compound and dead-end product reducing accumulation of reactive radical species. Apart from a specific role for XA in the signaling ca...

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Autores principales: Omar Taleb, Mohammed Maammar, Daniel Brumaru, Jean-Jacques Bourguignon, Martine Schmitt, Christian Klein, Véronique Kemmel, Michel Maitre, Ayikoe Guy Mensah-Nyagan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/66a5faffafe7420a847cbed2c658ef19
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