Most Caenorhabditis elegans microRNAs are individually not essential for development or viability.

MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We report the generation of deletion mutations in 87 miRNA genes in Caenorhabditis elegans, expanding the number of mutated miRNA genes to 95, or 8...

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Autores principales: Eric A Miska, Ezequiel Alvarez-Saavedra, Allison L Abbott, Nelson C Lau, Andrew B Hellman, Shannon M McGonagle, David P Bartel, Victor R Ambros, H Robert Horvitz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2007
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Acceso en línea:https://doaj.org/article/66adfa1501d9497e90c6c7944b050fa3
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