Evaluation of oxidant, antioxidant, and S100B levels in patients with conversion disorder

Hasan Büyükaslan,1 Sultan Basmacı Kandemir,2 Mehmet Asoğlu,3 Halil Kaya,4 Mehmet Tahir Gökdemir,1 İbrahim Fatih Karababa,3 Fatih Güngörmez,5 Fethiye Kılıçaslan,6 Emin Şavik7 1Department of Emergency Medicine, Faculty of Medicine, Harran Univer...

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Autores principales:	Büyükaslan H, Kandemir SB, Asoğlu M, Kaya H, Gökdemir MT, Karababa İF, Güngörmez F, Kılıçaslan F, Şavik E
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	Conversion disorder oxidative stress S100B Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/66b29855e7194507a4dc65e21c981ec0
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spelling	oai:doaj.org-article:66b29855e7194507a4dc65e21c981ec02021-12-02T05:25:18ZEvaluation of oxidant, antioxidant, and S100B levels in patients with conversion disorder1178-2021https://doaj.org/article/66b29855e7194507a4dc65e21c981ec02016-07-01T00:00:00Zhttps://www.dovepress.com/evaluation-of-oxidant-antioxidant-and-s100b-levels-in-patients-with-co-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Hasan Büyükaslan,1 Sultan Basmacı Kandemir,2 Mehmet Asoğlu,3 Halil Kaya,4 Mehmet Tahir Gökdemir,1 İbrahim Fatih Karababa,3 Fatih Güngörmez,5 Fethiye Kılıçaslan,6 Emin Şavik7 1Department of Emergency Medicine, Faculty of Medicine, Harran University, 2Department of Psychiatry, Balıklıgöl State Hospital, 3Department of Psychiatry, Faculty of Medicine, Harran University, Sanliurfa, 4Bursa Yüksek Ihtisas Training and Research Hospital, Bursa, 5Department of Emergency Medicine, Mehmet Akif İnan Research Hospital, 6Department of Child and Adolescent Psychiatry, 7Department of Biochemistry, Faculty of Medicine, Harran University, Sanliurfa, Turkey Introduction: Various psychodynamic, neurobiological, genetic, and sociocultural factors are believed to be involved in the etiology of conversion disorder (CD). Oxidative metabolism has been shown to deteriorate in association with many health problems and psychiatric disorders. We evaluated oxidative metabolism and S100B levels in the context of this multifactorial disease.Methods: Thirty-seven patients with CD (25 females and 12 males) and 42 healthy volunteers (21 females and 21 males), all matched for age and sex, were included in this study. The total oxidant status, total antioxidant status, oxidative stress index, and S100B levels were compared between the two groups.Results: The total oxidant status, oxidative stress index, and S100B levels were significantly higher in patients with CD than in the control group, whereas the total antioxidant status was significantly lower.Conclusion: CD is associated with deterioration of oxidative metabolism and increased neuronal damage. Keywords: conversion disorder, oxidative stress, S100BBüyükaslan HKandemir SBAsoğlu MKaya HGökdemir MTKarababa İFGüngörmez FKılıçaslan FŞavik EDove Medical PressarticleConversion disorderoxidative stressS100BNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2016, Iss Issue 1, Pp 1725-1729 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Conversion disorder oxidative stress S100B Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Conversion disorder oxidative stress S100B Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Büyükaslan H Kandemir SB Asoğlu M Kaya H Gökdemir MT Karababa İF Güngörmez F Kılıçaslan F Şavik E Evaluation of oxidant, antioxidant, and S100B levels in patients with conversion disorder
description	Hasan Büyükaslan,1 Sultan Basmacı Kandemir,2 Mehmet Asoğlu,3 Halil Kaya,4 Mehmet Tahir Gökdemir,1 İbrahim Fatih Karababa,3 Fatih Güngörmez,5 Fethiye Kılıçaslan,6 Emin Şavik7 1Department of Emergency Medicine, Faculty of Medicine, Harran University, 2Department of Psychiatry, Balıklıgöl State Hospital, 3Department of Psychiatry, Faculty of Medicine, Harran University, Sanliurfa, 4Bursa Yüksek Ihtisas Training and Research Hospital, Bursa, 5Department of Emergency Medicine, Mehmet Akif İnan Research Hospital, 6Department of Child and Adolescent Psychiatry, 7Department of Biochemistry, Faculty of Medicine, Harran University, Sanliurfa, Turkey Introduction: Various psychodynamic, neurobiological, genetic, and sociocultural factors are believed to be involved in the etiology of conversion disorder (CD). Oxidative metabolism has been shown to deteriorate in association with many health problems and psychiatric disorders. We evaluated oxidative metabolism and S100B levels in the context of this multifactorial disease.Methods: Thirty-seven patients with CD (25 females and 12 males) and 42 healthy volunteers (21 females and 21 males), all matched for age and sex, were included in this study. The total oxidant status, total antioxidant status, oxidative stress index, and S100B levels were compared between the two groups.Results: The total oxidant status, oxidative stress index, and S100B levels were significantly higher in patients with CD than in the control group, whereas the total antioxidant status was significantly lower.Conclusion: CD is associated with deterioration of oxidative metabolism and increased neuronal damage. Keywords: conversion disorder, oxidative stress, S100B
format	article
author	Büyükaslan H Kandemir SB Asoğlu M Kaya H Gökdemir MT Karababa İF Güngörmez F Kılıçaslan F Şavik E
author_facet	Büyükaslan H Kandemir SB Asoğlu M Kaya H Gökdemir MT Karababa İF Güngörmez F Kılıçaslan F Şavik E
author_sort	Büyükaslan H
title	Evaluation of oxidant, antioxidant, and S100B levels in patients with conversion disorder
title_short	Evaluation of oxidant, antioxidant, and S100B levels in patients with conversion disorder
title_full	Evaluation of oxidant, antioxidant, and S100B levels in patients with conversion disorder
title_fullStr	Evaluation of oxidant, antioxidant, and S100B levels in patients with conversion disorder
title_full_unstemmed	Evaluation of oxidant, antioxidant, and S100B levels in patients with conversion disorder
title_sort	evaluation of oxidant, antioxidant, and s100b levels in patients with conversion disorder
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/66b29855e7194507a4dc65e21c981ec0
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Evaluation of oxidant, antioxidant, and S100B levels in patients with conversion disorder

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