Generation of a chemical genetic model for JAK3

Generation of a chemical genetic model for JAK3

Abstract Janus Kinases (JAKs) have emerged as an important drug target for the treatment of a number of immune disorders due to the central role that they play in cytokine signalling. 4 isoforms of JAKs exist in mammalian cells and the ideal isoform profile of a JAK inhibitor has been the subject of...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Judit Remenyi, Rangeetha Jayaprakash Naik, Jinhua Wang, Momchil Razsolkov, Alyssa Verano, Quan Cai, Li Tan, Rachel Toth, Samantha Raggett, Carla Baillie, Ryan Traynor, C. James Hastie, Nathanael S. Gray, J. Simon C. Arthur
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/66b7f58af7964f179690d10510378958
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/66b7f58af7964f179690d10510378958

Ejemplares similares