Var2CSA minimal CSA binding region is located within the N-terminal region.

Var2CSA minimal CSA binding region is located within the N-terminal region.

Var2CSA, a key molecule linked with pregnancy-associated malaria (PAM), causes sequestration of Plasmodium falciparum infected erythrocytes (PEs) in the placenta by adhesion to chondroitin sulfate A (CSA). Var2CSA possesses a 300 kDa extracellular region composed of six Duffy-binding like (DBL) doma...

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Autores principales: Anand Srivastava, Stéphane Gangnard, Sébastien Dechavanne, Farroudja Amirat, Anita Lewit Bentley, Graham A Bentley, Benoît Gamain
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/66c2e98ae51745d387e6c420e2cdcbfb
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