Reconstruction of intestinal microecology of Type 2 diabetes by fecal microbiota transplantation: Why and how
Type 2 diabetes (T2D) is a chronic metabolic disease characterized by hyperglycemia due to insulin resistance. Mounting evidence has correlated T2D to alterations in the composition of gut microbiota. Accordingly, targeting the gut microbiota has become an emerging strategy for T2D management. The...
Guardado en:
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/66c4763f1065471fb5a2a4d7317c1317 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:66c4763f1065471fb5a2a4d7317c1317 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:66c4763f1065471fb5a2a4d7317c13172021-11-10T17:17:06ZReconstruction of intestinal microecology of Type 2 diabetes by fecal microbiota transplantation: Why and how10.17305/bjbms.2021.63231512-86011840-4812https://doaj.org/article/66c4763f1065471fb5a2a4d7317c13172021-11-01T00:00:00Zhttps://www.bjbms.org/ojs/index.php/bjbms/article/view/6323https://doaj.org/toc/1512-8601https://doaj.org/toc/1840-4812 Type 2 diabetes (T2D) is a chronic metabolic disease characterized by hyperglycemia due to insulin resistance. Mounting evidence has correlated T2D to alterations in the composition of gut microbiota. Accordingly, targeting the gut microbiota has become an emerging strategy for T2D management. The aim of this article is to get a better insight into the rationale for targeting gut microbiota in T2D treatment. Thus, we herein reviewed the change of gut microbiota composition in T2D, factors shaping gut microbiota, and potential mechanisms behind the contribution of gut microbiota to T2D pathogenesis. At present, it has become possible to use intestinal microorganism capsules, bacteria liquid, and other preparations to carry out fecal microbiota transplantation for the treatment and intervention of T2D with insulin resistance and immune-mediated Type 1 diabetes (T1D). Kaijian HouShuo ZhangZezhen WuDan ZhuFengwu ChenZi-Ning LeiWeiting LiuChuanxing XiaoZhe-Sheng ChenAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaarticleFecal Microbiota TransplantationType 2 diabetesintestinal microecologyMedicine (General)R5-920ENBosnian Journal of Basic Medical Sciences (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Fecal Microbiota Transplantation Type 2 diabetes intestinal microecology Medicine (General) R5-920 |
| spellingShingle |
Fecal Microbiota Transplantation Type 2 diabetes intestinal microecology Medicine (General) R5-920 Kaijian Hou Shuo Zhang Zezhen Wu Dan Zhu Fengwu Chen Zi-Ning Lei Weiting Liu Chuanxing Xiao Zhe-Sheng Chen Reconstruction of intestinal microecology of Type 2 diabetes by fecal microbiota transplantation: Why and how |
| description |
Type 2 diabetes (T2D) is a chronic metabolic disease characterized by hyperglycemia due to insulin resistance. Mounting evidence has correlated T2D to alterations in the composition of gut microbiota. Accordingly, targeting the gut microbiota has become an emerging strategy for T2D management. The aim of this article is to get a better insight into the rationale for targeting gut microbiota in T2D treatment. Thus, we herein reviewed the change of gut microbiota composition in T2D, factors shaping gut microbiota, and potential mechanisms behind the contribution of gut microbiota to T2D pathogenesis. At present, it has become possible to use intestinal microorganism capsules, bacteria liquid, and other preparations to carry out fecal microbiota transplantation for the treatment and intervention of T2D with insulin resistance and immune-mediated Type 1 diabetes (T1D).
|
| format |
article |
| author |
Kaijian Hou Shuo Zhang Zezhen Wu Dan Zhu Fengwu Chen Zi-Ning Lei Weiting Liu Chuanxing Xiao Zhe-Sheng Chen |
| author_facet |
Kaijian Hou Shuo Zhang Zezhen Wu Dan Zhu Fengwu Chen Zi-Ning Lei Weiting Liu Chuanxing Xiao Zhe-Sheng Chen |
| author_sort |
Kaijian Hou |
| title |
Reconstruction of intestinal microecology of Type 2 diabetes by fecal microbiota transplantation: Why and how |
| title_short |
Reconstruction of intestinal microecology of Type 2 diabetes by fecal microbiota transplantation: Why and how |
| title_full |
Reconstruction of intestinal microecology of Type 2 diabetes by fecal microbiota transplantation: Why and how |
| title_fullStr |
Reconstruction of intestinal microecology of Type 2 diabetes by fecal microbiota transplantation: Why and how |
| title_full_unstemmed |
Reconstruction of intestinal microecology of Type 2 diabetes by fecal microbiota transplantation: Why and how |
| title_sort |
reconstruction of intestinal microecology of type 2 diabetes by fecal microbiota transplantation: why and how |
| publisher |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| publishDate |
2021 |
| url |
https://doaj.org/article/66c4763f1065471fb5a2a4d7317c1317 |
| work_keys_str_mv |
AT kaijianhou reconstructionofintestinalmicroecologyoftype2diabetesbyfecalmicrobiotatransplantationwhyandhow AT shuozhang reconstructionofintestinalmicroecologyoftype2diabetesbyfecalmicrobiotatransplantationwhyandhow AT zezhenwu reconstructionofintestinalmicroecologyoftype2diabetesbyfecalmicrobiotatransplantationwhyandhow AT danzhu reconstructionofintestinalmicroecologyoftype2diabetesbyfecalmicrobiotatransplantationwhyandhow AT fengwuchen reconstructionofintestinalmicroecologyoftype2diabetesbyfecalmicrobiotatransplantationwhyandhow AT zininglei reconstructionofintestinalmicroecologyoftype2diabetesbyfecalmicrobiotatransplantationwhyandhow AT weitingliu reconstructionofintestinalmicroecologyoftype2diabetesbyfecalmicrobiotatransplantationwhyandhow AT chuanxingxiao reconstructionofintestinalmicroecologyoftype2diabetesbyfecalmicrobiotatransplantationwhyandhow AT zheshengchen reconstructionofintestinalmicroecologyoftype2diabetesbyfecalmicrobiotatransplantationwhyandhow |
| _version_ |
1718439876086464512 |