Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation

Summary: Neutrophil extracellular traps (NETs) have been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS) driven by viruses or bacteria, as well as in numerous immune-mediated disorders. Histone citrullination by the enzyme peptidylarginine deiminase 4 (PAD4) and the cons...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Valentina Poli, Victor Pui-Yan Ma, Marco Di Gioia, Achille Broggi, Mehdi Benamar, Qian Chen, Ralph Mazitschek, Stephen J. Haggarty, Talal A. Chatila, Jeffrey M. Karp, Ivan Zanoni
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/66d5caa429084e78b167076bd43525f3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!