Chemotaxing neutrophils enter alternate branches at capillary bifurcations

Neutrophils mobilize rapidly and travel through the vasculature and microcirculation en masse in response to inflammatory stimuli. Here the authors use a microfluidic device and intravital microscopy to show neutrophils move through tissues in a highly ordered pattern, taking turns to file into alte...

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Autores principales: Xiao Wang, Mokarram Hossain, Ania Bogoslowski, Paul Kubes, Daniel Irimia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/66e0f2cdb49c492393495e7c37afdc29
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Sumario:Neutrophils mobilize rapidly and travel through the vasculature and microcirculation en masse in response to inflammatory stimuli. Here the authors use a microfluidic device and intravital microscopy to show neutrophils move through tissues in a highly ordered pattern, taking turns to file into alternate branches at bifurcations.