Elucidating the genetic architecture of reproductive ageing in the Japanese population
The timing of female reproductive capacity is influenced by genetic and environmental factors. Here, in genome-wide association studies, the authors identify genetic loci for age at menarche and onset of menopause in Japanese women, and highlight differences with European populations.
Guardado en:
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/66e1258d1fd84ee49edcd0abf3476652 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:66e1258d1fd84ee49edcd0abf3476652 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:66e1258d1fd84ee49edcd0abf34766522021-12-02T14:39:27ZElucidating the genetic architecture of reproductive ageing in the Japanese population10.1038/s41467-018-04398-z2041-1723https://doaj.org/article/66e1258d1fd84ee49edcd0abf34766522018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04398-zhttps://doaj.org/toc/2041-1723The timing of female reproductive capacity is influenced by genetic and environmental factors. Here, in genome-wide association studies, the authors identify genetic loci for age at menarche and onset of menopause in Japanese women, and highlight differences with European populations.Momoko HorikoshiFelix R. DayMasato AkiyamaMakoto HirataYoichiro KamataniKoichi MatsudaKazuyoshi IshigakiMasahiro KanaiHollis WrightCarlos A. ToroSergio R. OjedaAlejandro LomnicziMichiaki KuboKen K. OngJohn. R. B. PerryNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Momoko Horikoshi Felix R. Day Masato Akiyama Makoto Hirata Yoichiro Kamatani Koichi Matsuda Kazuyoshi Ishigaki Masahiro Kanai Hollis Wright Carlos A. Toro Sergio R. Ojeda Alejandro Lomniczi Michiaki Kubo Ken K. Ong John. R. B. Perry Elucidating the genetic architecture of reproductive ageing in the Japanese population |
description |
The timing of female reproductive capacity is influenced by genetic and environmental factors. Here, in genome-wide association studies, the authors identify genetic loci for age at menarche and onset of menopause in Japanese women, and highlight differences with European populations. |
format |
article |
author |
Momoko Horikoshi Felix R. Day Masato Akiyama Makoto Hirata Yoichiro Kamatani Koichi Matsuda Kazuyoshi Ishigaki Masahiro Kanai Hollis Wright Carlos A. Toro Sergio R. Ojeda Alejandro Lomniczi Michiaki Kubo Ken K. Ong John. R. B. Perry |
author_facet |
Momoko Horikoshi Felix R. Day Masato Akiyama Makoto Hirata Yoichiro Kamatani Koichi Matsuda Kazuyoshi Ishigaki Masahiro Kanai Hollis Wright Carlos A. Toro Sergio R. Ojeda Alejandro Lomniczi Michiaki Kubo Ken K. Ong John. R. B. Perry |
author_sort |
Momoko Horikoshi |
title |
Elucidating the genetic architecture of reproductive ageing in the Japanese population |
title_short |
Elucidating the genetic architecture of reproductive ageing in the Japanese population |
title_full |
Elucidating the genetic architecture of reproductive ageing in the Japanese population |
title_fullStr |
Elucidating the genetic architecture of reproductive ageing in the Japanese population |
title_full_unstemmed |
Elucidating the genetic architecture of reproductive ageing in the Japanese population |
title_sort |
elucidating the genetic architecture of reproductive ageing in the japanese population |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/66e1258d1fd84ee49edcd0abf3476652 |
work_keys_str_mv |
AT momokohorikoshi elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT felixrday elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT masatoakiyama elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT makotohirata elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT yoichirokamatani elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT koichimatsuda elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT kazuyoshiishigaki elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT masahirokanai elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT holliswright elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT carlosatoro elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT sergiorojeda elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT alejandrolomniczi elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT michiakikubo elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT kenkong elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation AT johnrbperry elucidatingthegeneticarchitectureofreproductiveageinginthejapanesepopulation |
_version_ |
1718390594704769024 |