Elucidating the genetic architecture of reproductive ageing in the Japanese population

The timing of female reproductive capacity is influenced by genetic and environmental factors. Here, in genome-wide association studies, the authors identify genetic loci for age at menarche and onset of menopause in Japanese women, and highlight differences with European populations.

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Autores principales: Momoko Horikoshi, Felix R. Day, Masato Akiyama, Makoto Hirata, Yoichiro Kamatani, Koichi Matsuda, Kazuyoshi Ishigaki, Masahiro Kanai, Hollis Wright, Carlos A. Toro, Sergio R. Ojeda, Alejandro Lomniczi, Michiaki Kubo, Ken K. Ong, John. R. B. Perry
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/66e1258d1fd84ee49edcd0abf3476652
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spelling oai:doaj.org-article:66e1258d1fd84ee49edcd0abf34766522021-12-02T14:39:27ZElucidating the genetic architecture of reproductive ageing in the Japanese population10.1038/s41467-018-04398-z2041-1723https://doaj.org/article/66e1258d1fd84ee49edcd0abf34766522018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04398-zhttps://doaj.org/toc/2041-1723The timing of female reproductive capacity is influenced by genetic and environmental factors. Here, in genome-wide association studies, the authors identify genetic loci for age at menarche and onset of menopause in Japanese women, and highlight differences with European populations.Momoko HorikoshiFelix R. DayMasato AkiyamaMakoto HirataYoichiro KamataniKoichi MatsudaKazuyoshi IshigakiMasahiro KanaiHollis WrightCarlos A. ToroSergio R. OjedaAlejandro LomnicziMichiaki KuboKen K. OngJohn. R. B. PerryNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Momoko Horikoshi
Felix R. Day
Masato Akiyama
Makoto Hirata
Yoichiro Kamatani
Koichi Matsuda
Kazuyoshi Ishigaki
Masahiro Kanai
Hollis Wright
Carlos A. Toro
Sergio R. Ojeda
Alejandro Lomniczi
Michiaki Kubo
Ken K. Ong
John. R. B. Perry
Elucidating the genetic architecture of reproductive ageing in the Japanese population
description The timing of female reproductive capacity is influenced by genetic and environmental factors. Here, in genome-wide association studies, the authors identify genetic loci for age at menarche and onset of menopause in Japanese women, and highlight differences with European populations.
format article
author Momoko Horikoshi
Felix R. Day
Masato Akiyama
Makoto Hirata
Yoichiro Kamatani
Koichi Matsuda
Kazuyoshi Ishigaki
Masahiro Kanai
Hollis Wright
Carlos A. Toro
Sergio R. Ojeda
Alejandro Lomniczi
Michiaki Kubo
Ken K. Ong
John. R. B. Perry
author_facet Momoko Horikoshi
Felix R. Day
Masato Akiyama
Makoto Hirata
Yoichiro Kamatani
Koichi Matsuda
Kazuyoshi Ishigaki
Masahiro Kanai
Hollis Wright
Carlos A. Toro
Sergio R. Ojeda
Alejandro Lomniczi
Michiaki Kubo
Ken K. Ong
John. R. B. Perry
author_sort Momoko Horikoshi
title Elucidating the genetic architecture of reproductive ageing in the Japanese population
title_short Elucidating the genetic architecture of reproductive ageing in the Japanese population
title_full Elucidating the genetic architecture of reproductive ageing in the Japanese population
title_fullStr Elucidating the genetic architecture of reproductive ageing in the Japanese population
title_full_unstemmed Elucidating the genetic architecture of reproductive ageing in the Japanese population
title_sort elucidating the genetic architecture of reproductive ageing in the japanese population
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/66e1258d1fd84ee49edcd0abf3476652
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