Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation

Abstract Microglia are integral mediators of innate immunity within the mammalian central nervous system. Typical microglial responses are transient, intending to restore homeostasis by orchestrating the removal of pathogens and debris and the regeneration of damaged neurons. However, prolonged and...

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Bibliographic Details
Main Authors: Erskine Chu, Richelle Mychasiuk, Margaret L. Hibbs, Bridgette D. Semple
Format: article
Language:EN
Published: BMC 2021
Subjects:
AKT
Online Access:https://doaj.org/article/66e416b4e60b47ce875018a43baf08b7
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