Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation

Abstract Microglia are integral mediators of innate immunity within the mammalian central nervous system. Typical microglial responses are transient, intending to restore homeostasis by orchestrating the removal of pathogens and debris and the regeneration of damaged neurons. However, prolonged and...

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Autores principales: Erskine Chu, Richelle Mychasiuk, Margaret L. Hibbs, Bridgette D. Semple
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
AKT
Acceso en línea:https://doaj.org/article/66e416b4e60b47ce875018a43baf08b7
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