Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains

Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains

ABSTRACT Bacterial SH3 (SH3b) domains are commonly fused with papain-like Nlp/P60 cell wall hydrolase domains. To understand how the modular architecture of SH3b and NlpC/P60 affects the activity of the catalytic domain, three putative NlpC/P60 cell wall hydrolases were biochemically and structurall...

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Main Authors: Qingping Xu, Dominique Mengin-Lecreulx, Xueqian W. Liu, Delphine Patin, Carol L. Farr, Joanna C. Grant, Hsiu-Ju Chiu, Lukasz Jaroszewski, Mark W. Knuth, Adam Godzik, Scott A. Lesley, Marc-André Elsliger, Ashley M. Deacon, Ian A. Wilson
Format: article
Language:EN
Published: American Society for Microbiology 2015
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/66e5fd174c9b48308e36f26975b3b4c4
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https://doaj.org/article/66e5fd174c9b48308e36f26975b3b4c4

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