FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

In this study the authors identify a possible link between the gene FAM222A and brain atrophy. The protein it encodes is found to accumulate in plaques seen in Alzheimer’s disease, and functional analysis suggests it interacts with amyloid-beta.

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Auteurs principaux:	Tingxiang Yan, Jingjing Liang, Ju Gao, Luwen Wang, Hisashi Fujioka, The Alzheimer Disease Neuroimaging Initiative, Xiaofeng Zhu, Xinglong Wang
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2020
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/66e7f9458509400dbf719f0fee7a5e25
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id	oai:doaj.org-article:66e7f9458509400dbf719f0fee7a5e25
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spelling	oai:doaj.org-article:66e7f9458509400dbf719f0fee7a5e252021-12-02T15:39:23ZFAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease10.1038/s41467-019-13962-02041-1723https://doaj.org/article/66e7f9458509400dbf719f0fee7a5e252020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13962-0https://doaj.org/toc/2041-1723In this study the authors identify a possible link between the gene FAM222A and brain atrophy. The protein it encodes is found to accumulate in plaques seen in Alzheimer’s disease, and functional analysis suggests it interacts with amyloid-beta.Tingxiang YanJingjing LiangJu GaoLuwen WangHisashi FujiokaThe Alzheimer Disease Neuroimaging InitiativeXiaofeng ZhuXinglong WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tingxiang Yan Jingjing Liang Ju Gao Luwen Wang Hisashi Fujioka The Alzheimer Disease Neuroimaging Initiative Xiaofeng Zhu Xinglong Wang FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease
description	In this study the authors identify a possible link between the gene FAM222A and brain atrophy. The protein it encodes is found to accumulate in plaques seen in Alzheimer’s disease, and functional analysis suggests it interacts with amyloid-beta.
format	article
author	Tingxiang Yan Jingjing Liang Ju Gao Luwen Wang Hisashi Fujioka The Alzheimer Disease Neuroimaging Initiative Xiaofeng Zhu Xinglong Wang
author_facet	Tingxiang Yan Jingjing Liang Ju Gao Luwen Wang Hisashi Fujioka The Alzheimer Disease Neuroimaging Initiative Xiaofeng Zhu Xinglong Wang
author_sort	Tingxiang Yan
title	FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease
title_short	FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease
title_full	FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease
title_fullStr	FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease
title_full_unstemmed	FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease
title_sort	fam222a encodes a protein which accumulates in plaques in alzheimer’s disease
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/66e7f9458509400dbf719f0fee7a5e25
work_keys_str_mv	AT tingxiangyan fam222aencodesaproteinwhichaccumulatesinplaquesinalzheimersdisease AT jingjingliang fam222aencodesaproteinwhichaccumulatesinplaquesinalzheimersdisease AT jugao fam222aencodesaproteinwhichaccumulatesinplaquesinalzheimersdisease AT luwenwang fam222aencodesaproteinwhichaccumulatesinplaquesinalzheimersdisease AT hisashifujioka fam222aencodesaproteinwhichaccumulatesinplaquesinalzheimersdisease AT thealzheimerdiseaseneuroimaginginitiative fam222aencodesaproteinwhichaccumulatesinplaquesinalzheimersdisease AT xiaofengzhu fam222aencodesaproteinwhichaccumulatesinplaquesinalzheimersdisease AT xinglongwang fam222aencodesaproteinwhichaccumulatesinplaquesinalzheimersdisease
_version_	1718385936445734912

FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

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