Controllable protein phase separation and modular recruitment to form responsive membraneless organelles

Designer organelles with new biochemical functionalities are of great interest in synthetic biology and cellular engineering. Here the authors present a single-protein-based platform for generating synthetic membraneless compartments that is capable of enzymatically-triggered alterations to phase be...

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Autores principales:	Benjamin S. Schuster, Ellen H. Reed, Ranganath Parthasarathy, Craig N. Jahnke, Reese M. Caldwell, Jessica G. Bermudez, Holly Ramage, Matthew C. Good, Daniel A. Hammer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/66e8162a85c44e12a7eb131604d160da
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spelling	oai:doaj.org-article:66e8162a85c44e12a7eb131604d160da2021-12-02T14:39:23ZControllable protein phase separation and modular recruitment to form responsive membraneless organelles10.1038/s41467-018-05403-12041-1723https://doaj.org/article/66e8162a85c44e12a7eb131604d160da2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05403-1https://doaj.org/toc/2041-1723Designer organelles with new biochemical functionalities are of great interest in synthetic biology and cellular engineering. Here the authors present a single-protein-based platform for generating synthetic membraneless compartments that is capable of enzymatically-triggered alterations to phase behavior and of recruiting and concentrating cargo proteins.Benjamin S. SchusterEllen H. ReedRanganath ParthasarathyCraig N. JahnkeReese M. CaldwellJessica G. BermudezHolly RamageMatthew C. GoodDaniel A. HammerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Benjamin S. Schuster Ellen H. Reed Ranganath Parthasarathy Craig N. Jahnke Reese M. Caldwell Jessica G. Bermudez Holly Ramage Matthew C. Good Daniel A. Hammer Controllable protein phase separation and modular recruitment to form responsive membraneless organelles
description	Designer organelles with new biochemical functionalities are of great interest in synthetic biology and cellular engineering. Here the authors present a single-protein-based platform for generating synthetic membraneless compartments that is capable of enzymatically-triggered alterations to phase behavior and of recruiting and concentrating cargo proteins.
format	article
author	Benjamin S. Schuster Ellen H. Reed Ranganath Parthasarathy Craig N. Jahnke Reese M. Caldwell Jessica G. Bermudez Holly Ramage Matthew C. Good Daniel A. Hammer
author_facet	Benjamin S. Schuster Ellen H. Reed Ranganath Parthasarathy Craig N. Jahnke Reese M. Caldwell Jessica G. Bermudez Holly Ramage Matthew C. Good Daniel A. Hammer
author_sort	Benjamin S. Schuster
title	Controllable protein phase separation and modular recruitment to form responsive membraneless organelles
title_short	Controllable protein phase separation and modular recruitment to form responsive membraneless organelles
title_full	Controllable protein phase separation and modular recruitment to form responsive membraneless organelles
title_fullStr	Controllable protein phase separation and modular recruitment to form responsive membraneless organelles
title_full_unstemmed	Controllable protein phase separation and modular recruitment to form responsive membraneless organelles
title_sort	controllable protein phase separation and modular recruitment to form responsive membraneless organelles
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/66e8162a85c44e12a7eb131604d160da
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_version_	1718390657923416064

Controllable protein phase separation and modular recruitment to form responsive membraneless organelles

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