Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant <i>Enterobacterales</i> in the United States

Heteroresistance is an underappreciated phenomenon that may be the cause of some unexplained antibiotic treatment failures. Misclassification of heteroresistant isolates as susceptible may lead to inappropriate therapy.

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Autores principales: Victor I. Band, Sarah W. Satola, Richard D. Smith, David A. Hufnagel, Chris Bower, Andrew B. Conley, Lavanya Rishishwar, Suzanne E. Dale, Dwight J. Hardy, Roberto L. Vargas, Ghinwa Dumyati, Marion A. Kainer, Erin C. Phipps, Rebecca Pierce, Lucy E. Wilson, Matthew Sorensen, Erik Nilsson, I. King Jordan, Eileen M. Burd, Monica M. Farley, Jesse T. Jacob, Robert K. Ernst, David S. Weiss
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Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/66ed1c01ff83414ba325c4ef742f6f0e
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spelling oai:doaj.org-article:66ed1c01ff83414ba325c4ef742f6f0e2021-11-03T18:15:38Z Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant <i>Enterobacterales</i> in the United States 2161-21292150-751110.1128/mBio.02881-20https://doaj.org/article/66ed1c01ff83414ba325c4ef742f6f0e2021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02881-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 Heteroresistance is an underappreciated phenomenon that may be the cause of some unexplained antibiotic treatment failures. Misclassification of heteroresistant isolates as susceptible may lead to inappropriate therapy.Victor I. BandSarah W. SatolaRichard D. SmithDavid A. HufnagelChris BowerAndrew B. ConleyLavanya RishishwarSuzanne E. DaleDwight J. HardyRoberto L. VargasGhinwa DumyatiMarion A. KainerErin C. PhippsRebecca PierceLucy E. WilsonMatthew SorensenErik NilssonI. King JordanEileen M. BurdMonica M. FarleyJesse T. JacobRobert K. ErnstDavid S. WeissAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Victor I. Band
Sarah W. Satola
Richard D. Smith
David A. Hufnagel
Chris Bower
Andrew B. Conley
Lavanya Rishishwar
Suzanne E. Dale
Dwight J. Hardy
Roberto L. Vargas
Ghinwa Dumyati
Marion A. Kainer
Erin C. Phipps
Rebecca Pierce
Lucy E. Wilson
Matthew Sorensen
Erik Nilsson
I. King Jordan
Eileen M. Burd
Monica M. Farley
Jesse T. Jacob
Robert K. Ernst
David S. Weiss
Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant <i>Enterobacterales</i> in the United States
description Heteroresistance is an underappreciated phenomenon that may be the cause of some unexplained antibiotic treatment failures. Misclassification of heteroresistant isolates as susceptible may lead to inappropriate therapy.
format article
author Victor I. Band
Sarah W. Satola
Richard D. Smith
David A. Hufnagel
Chris Bower
Andrew B. Conley
Lavanya Rishishwar
Suzanne E. Dale
Dwight J. Hardy
Roberto L. Vargas
Ghinwa Dumyati
Marion A. Kainer
Erin C. Phipps
Rebecca Pierce
Lucy E. Wilson
Matthew Sorensen
Erik Nilsson
I. King Jordan
Eileen M. Burd
Monica M. Farley
Jesse T. Jacob
Robert K. Ernst
David S. Weiss
author_facet Victor I. Band
Sarah W. Satola
Richard D. Smith
David A. Hufnagel
Chris Bower
Andrew B. Conley
Lavanya Rishishwar
Suzanne E. Dale
Dwight J. Hardy
Roberto L. Vargas
Ghinwa Dumyati
Marion A. Kainer
Erin C. Phipps
Rebecca Pierce
Lucy E. Wilson
Matthew Sorensen
Erik Nilsson
I. King Jordan
Eileen M. Burd
Monica M. Farley
Jesse T. Jacob
Robert K. Ernst
David S. Weiss
author_sort Victor I. Band
title Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant <i>Enterobacterales</i> in the United States
title_short Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant <i>Enterobacterales</i> in the United States
title_full Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant <i>Enterobacterales</i> in the United States
title_fullStr Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant <i>Enterobacterales</i> in the United States
title_full_unstemmed Colistin Heteroresistance Is Largely Undetected among Carbapenem-Resistant <i>Enterobacterales</i> in the United States
title_sort colistin heteroresistance is largely undetected among carbapenem-resistant <i>enterobacterales</i> in the united states
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/66ed1c01ff83414ba325c4ef742f6f0e
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