Gambogic acid-loaded magnetic Fe3O4 nanoparticles inhibit Panc-1 pancreatic cancer cell proliferation and migration by inactivating transcription factor ETS1

QR Code

Gambogic acid-loaded magnetic Fe3O4 nanoparticles inhibit Panc-1 pancreatic cancer cell proliferation and migration by inactivating transcription factor ETS1

Cailian Wang1, Haijun Zhang1, Yan Chen1, Fangfang Shi1, Baoan Chen2,31Department of Oncology, 2Department of Hematology, Zhongda Hospital, 3Faculty of Oncology, Medical School, Southeast University, Nanjing, People&rsquo;s Republic of ChinaBackground: E26 transformation-specific sequence-1 (...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Wang C, Zhang H, Chen Y, Shi F, Chen B
Format:	article
Langue:	EN
Publié:	Dove Medical Press 2012
Sujets:	Medicine (General) R5-920
Accès en ligne:	https://doaj.org/article/66fc1ffd69f54af69950101e52ea1c3c
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Study of the enhanced anticancer efficacy of gambogic acid on Capan-1 pancreatic cancer cells when mediated via magnetic Fe3O4 nanoparticles
par: Wang C, et autres
Publié: (2011)

Activation of a Ductal-to-Endocrine Transdifferentiation Transcriptional Program in the Pancreatic Cancer Cell Line PANC-1 Is Controlled by RAC1 and RAC1b through Antagonistic Regulation of Stemness Factors
par: Paula Marie Schmidtlein, et autres
Publié: (2021)

Synergistic effect of magnetic nanoparticles of Fe3O4 with gambogic acid on apoptosis of K562 leukemia cells
par: Baoan Chen, et autres
Publié: (2009)

Gambogic acid-loaded biomimetic nanoparticles in colorectal cancer treatment
par: Zhang Z, et autres
Publié: (2017)

Synergetic effect of functional cadmium–tellurium quantum dots conjugated with gambogic acid for HepG2 cell-labeling and proliferation inhibition
par: Xu P, et autres
Publié: (2013)

The association of transcription factor Prox1 with the proliferation, migration, and invasion of lung cancer
par: Hao Xinxin, et autres
Publié: (2021)

Transcription factor KLF15 inhibits the proliferation and migration of gastric cancer cells via regulating the TFAP2A-AS1/NISCH axis
par: Xin Zhao, et autres
Publié: (2021)

Disulfiram-loaded porous PLGA microparticle for inhibiting the proliferation and migration of non-small-cell lung cancer
par: Wang C, et autres
Publié: (2017)

LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling
par: Xudong Huang, et autres
Publié: (2021)

Oridonin nanosuspension was more effective than free oridonin on G2/M cell cycle arrest and apoptosis in the human pancreatic cancer PANC-1 cell line
par: Qi XL, et autres
Publié: (2012)

MK8722, an AMPK activator, inhibiting carcinoma proliferation, invasion and migration in human pancreatic cancer cells
par: Cheng Wang, et autres
Publié: (2021)

CRTAC1 (Cartilage acidic protein 1) inhibits cell proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) process in bladder cancer by downregulating Yin Yang 1 (YY1) to inactivate the TGF-β pathway
par: Jianghua Yang, et autres
Publié: (2021)

Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathway
par: Shangfeng Gao, et autres
Publié: (2017)

ATG4B Inhibitor UAMC-2526 Potentiates the Chemotherapeutic Effect of Gemcitabine in a Panc02 Mouse Model of Pancreatic Ductal Adenocarcinoma
par: Farnaz Sedigheh Takhsha, et autres
Publié: (2021)

Gambogic Acid as a Candidate for Cancer Therapy: A Review
par: Liu Y, et autres
Publié: (2020)

Curcumin-loaded galactosylated BSA nanoparticles as targeted drug delivery carriers inhibit hepatocellular carcinoma cell proliferation and migration
par: Huang Y, et autres
Publié: (2018)

Dehydrocorydaline Inhibits Cell Proliferation, Migration and Invasion via Suppressing MEK1/2-ERK1/2 Cascade in Melanoma [Corrigendum]
par: Hu H, et autres
Publié: (2021)

Inducing cell cycle arrest and apoptosis by dimercaptosuccinic acid modified Fe3O4 magnetic nanoparticles combined with nontoxic concentration of bortezomib and gambogic acid in RPMI-8226 cells
par: Zhang W, et autres
Publié: (2015)

Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming
par: Yohan Suryo Rahmanto, et autres
Publié: (2020)

Absent in melanoma 2 suppresses gastric cancer cell proliferation and migration via inactivation of AKT signaling pathway
par: Dong Wang, et autres
Publié: (2021)

HIG1 domain family member 1A disrupts proliferation, migration and invasion of colon adenocarcinoma cells
par: Zhenyu Xu, et autres
Publié: (2021)

High expression of AKR1C1 is associated with proliferation and migration of small-cell lung cancer cells
par: Tian H, et autres
Publié: (2016)

Characterization and Anti-Cancerous Effect of Putranjiva roxburghii Seed Extract Mediated Silver Nanoparticles on Human Colon (HCT-116), Pancreatic (PANC-1) and Breast (MDA-MB 231) Cancer Cell Lines: A Comparative Study
par: Balkrishna A, et autres
Publié: (2020)

Synergistic effect of a combination of nanoparticulate Fe3O4 and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells
par: Hu S, et autres
Publié: (2012)

LBX2-AS1 Activates FSTL3 by Binding to Transcription Factor RARα to Foster Proliferation, Migration, and Invasion of Thyroid Cancer
par: Jia Li, et autres
Publié: (2021)

Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer
par: Chaozhong Peng, et autres
Publié: (2021)

BART inhibits pancreatic cancer cell invasion by PKCα inactivation through binding to ANX7.
par: Keisuke Taniuchi, et autres
Publié: (2012)

Strong 3D and 1D magnetism in hexagonal Fe-chalcogenides FeS and FeSe vs. weak magnetism in hexagonal FeTe
par: David S. Parker
Publié: (2017)

Gambogic amide inhibits angiogenesis by suppressing VEGF/VEGFR2 in endothelial cells in a TrkA-independent manner
par: Tongtong Sui, et autres
Publié: (2021)

Inhibition of cell proliferation and migration through nucleobase-modified polyamidoamine-mediated p53 delivery
par: Han H, et autres
Publié: (2018)

Oridonin-loaded and GPC1-targeted gold nanoparticles for multimodal imaging and therapy in pancreatic cancer
par: Qiu W, et autres
Publié: (2018)

Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes
par: Hiroki Sugishita, et autres
Publié: (2021)

Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation
par: Sandra Heller, et autres
Publié: (2021)

CircRNA circ_0004370 promotes cell proliferation, migration, and invasion and inhibits cell apoptosis of esophageal cancer via miR-1301-3p/COL1A1 axis
par: Chen Xiaobo, et autres
Publié: (2021)

Inhibition of SIRT1 combined with gemcitabine therapy for pancreatic carcinoma
par: Gong DJ, et autres
Publié: (2013)

Improving aqueous solubility and antitumor effects by nanosized gambogic acid-mPEG2000 micelles
par: Cai LL, et autres
Publié: (2013)

Increased apoptosis, but not pancreatic duodenal homeobox-1 expression in pancreatic islets is associated with intermittent glucose loads in mice
par: Lilik Herawati, et autres
Publié: (2018)

Inhibition of hypoxic response decreases stemness and reduces tumorigenic signaling due to impaired assembly of HIF1 transcription complex in pancreatic cancer
par: Olivia McGinn, et autres
Publié: (2017)

Inhibition of HIV-1 gene transcription by KAP1 in myeloid lineage
par: Amina Ait-Ammar, et autres
Publié: (2021)

Inhibition of Glioma Cells’ Proliferation by Doxorubicin-Loaded Exosomes via Microfluidics
par: Thakur A, et autres
Publié: (2020)