Communication pathways bridge local and global conformations in an IgG4 antibody
Abstract The affinity of an antibody for its antigen is primarily determined by the specific sequence and structural arrangement of the complementarity-determining regions (CDRs). Recent evidence, however, points toward a nontrivial relation between the CDR and distal sites: variations in the bindin...
Guardado en:
Autores principales: | Thomas Tarenzi, Marta Rigoli, Raffaello Potestio |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/66ff6bb769b24adb806d3721acdfc7ae |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Nanoscale spatial dependence of avidity in an IgG1 antibody
por: Agnieszka Jendroszek, et al.
Publicado: (2021) -
Impact of Antigen Density on the Binding Mechanism of IgG Antibodies
por: Maya Hadzhieva, et al.
Publicado: (2017) -
Cytoprotective IgG antibodies in sera from a subset of patients with AQP4-IgG seropositive neuromyelitis optica spectrum disorder
por: Lukmanee Tradtrantip, et al.
Publicado: (2021) -
Assignment of Serotype-Specific IgG1, IgG2, and IgA Weight-Based Antibody Units to the Human Pneumococcal Standard Reference Serum, 007sp
por: Scott Jones, et al.
Publicado: (2019) -
A new approach to produce IgG4-like bispecific antibodies
por: Caizhi Zhao, et al.
Publicado: (2021)