Arrestins contribute to amyloid beta-induced cell death via modulation of autophagy and the α7nAch receptor in SH-SY5Y cells
Abstract Amyloid β-protein (Aβ) is believed to contribute to the development of Alzheimer’s disease (AD). Here we showed that Aβ25-35 rapidly caused activation of autophagy, subsequently leading to reduction of autophagy associated with cellular apoptosis. Further investigation revealed that the acc...
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Autores principales: | Yi-qing Liu, Meng-qi Jia, Zhao-hong Xie, Xiao-fei Liu, Hui-Yang, Xiao-lei Zheng, Hui-qing Yuan, Jian-zhong Bi |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/67019f06892b4c4e970964bf203f83e3 |
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