Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation

Interorganelle membrane contact sites between the endoplasmic reticulum and the endolysosome. Here, the authors show that ER-endolysosome membrane contact sites are promoted by the proteins protrudin and PDZD8 and may contribute to lipid extraction at these contact sites.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Michiko Shirane, Mariko Wada, Keiko Morita, Nahoki Hayashi, Reina Kunimatsu, Yuki Matsumoto, Fumiko Matsuzaki, Hirokazu Nakatsumi, Keisuke Ohta, Yasushi Tamura, Keiichi I. Nakayama
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Q
Accès en ligne:https://doaj.org/article/670432a918664d32a912916b09eded29
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!