Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation

Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation

Interorganelle membrane contact sites between the endoplasmic reticulum and the endolysosome. Here, the authors show that ER-endolysosome membrane contact sites are promoted by the proteins protrudin and PDZD8 and may contribute to lipid extraction at these contact sites.

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Detalles Bibliográficos
Autores principales: Michiko Shirane, Mariko Wada, Keiko Morita, Nahoki Hayashi, Reina Kunimatsu, Yuki Matsumoto, Fumiko Matsuzaki, Hirokazu Nakatsumi, Keisuke Ohta, Yasushi Tamura, Keiichi I. Nakayama
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/670432a918664d32a912916b09eded29
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