A comparative two-cohort study of pediatric patients with long term stay in ICUs

Abstract During the last decades, the number of patients with long stay admissions (LSA) in PICU has increased. The purpose of this study was to identify factors associated with PICU LSA, assessing healthcare resources use and changes in the profile of these patients. A retrospective, observational,...

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Autores principales:	Julia García Mancebo, Sara de la Mata Navazo, Estíbaliz López-Herce Arteta, Rosario Montero Mateo, Isabel María López Esteban, Adriana Mazzuchelli Domínguez, María Sánchez Doutel, Jesús López-Herce Cid, Rafael González Cortés
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6711fcda15bb45f1924485ba06cd6d98
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spelling	oai:doaj.org-article:6711fcda15bb45f1924485ba06cd6d982021-12-02T13:34:31ZA comparative two-cohort study of pediatric patients with long term stay in ICUs10.1038/s41598-021-84248-z2045-2322https://doaj.org/article/6711fcda15bb45f1924485ba06cd6d982021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-84248-zhttps://doaj.org/toc/2045-2322Abstract During the last decades, the number of patients with long stay admissions (LSA) in PICU has increased. The purpose of this study was to identify factors associated with PICU LSA, assessing healthcare resources use and changes in the profile of these patients. A retrospective, observational, single-center study was carried out. Characteristics of LSA were compared between two periods (2006–2010 and 2011–2015). During the earlier period there were 2,118 admissions (3.9% of them LSA), whereas during the second period, there were 1,763 (5.4% of them LSA) (p = 0.025). LSA accounted for 33.7% PICU stay days during the first period and 46.7% during the second (p < 0.001). Higher use of non-invasive ventilation (80.2% vs. 37.8%, p = 0.001) and high-flow oxygen therapy (68.8% vs. 37.8%, p = 0.005) was observed in the 2011–2015 cohort, whereas the use of arterial catheter (77.1% vs. 92.6%, p = 0.005), continuous infusion of adrenaline (55.2% vs. 75.9%, p = 0.004), and hemoderivative transfusion (74% vs. 89.2%, p = 0.010) was less frequent. In the 2006–2010 cohort, hospital-acquired infections were more common (95.2% vs. 68.8%, p < 0.001) and mortality was higher (26.8% vs. 13.8%, p = 0.026). The number of long-stay PICU admissions have increased entailing an intensive use of healthcare resources. These patients have a high risk for complications and mortality.Julia García ManceboSara de la Mata NavazoEstíbaliz López-Herce ArtetaRosario Montero MateoIsabel María López EstebanAdriana Mazzuchelli DomínguezMaría Sánchez DoutelJesús López-Herce CidRafael González CortésNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Julia García Mancebo Sara de la Mata Navazo Estíbaliz López-Herce Arteta Rosario Montero Mateo Isabel María López Esteban Adriana Mazzuchelli Domínguez María Sánchez Doutel Jesús López-Herce Cid Rafael González Cortés A comparative two-cohort study of pediatric patients with long term stay in ICUs
description	Abstract During the last decades, the number of patients with long stay admissions (LSA) in PICU has increased. The purpose of this study was to identify factors associated with PICU LSA, assessing healthcare resources use and changes in the profile of these patients. A retrospective, observational, single-center study was carried out. Characteristics of LSA were compared between two periods (2006–2010 and 2011–2015). During the earlier period there were 2,118 admissions (3.9% of them LSA), whereas during the second period, there were 1,763 (5.4% of them LSA) (p = 0.025). LSA accounted for 33.7% PICU stay days during the first period and 46.7% during the second (p < 0.001). Higher use of non-invasive ventilation (80.2% vs. 37.8%, p = 0.001) and high-flow oxygen therapy (68.8% vs. 37.8%, p = 0.005) was observed in the 2011–2015 cohort, whereas the use of arterial catheter (77.1% vs. 92.6%, p = 0.005), continuous infusion of adrenaline (55.2% vs. 75.9%, p = 0.004), and hemoderivative transfusion (74% vs. 89.2%, p = 0.010) was less frequent. In the 2006–2010 cohort, hospital-acquired infections were more common (95.2% vs. 68.8%, p < 0.001) and mortality was higher (26.8% vs. 13.8%, p = 0.026). The number of long-stay PICU admissions have increased entailing an intensive use of healthcare resources. These patients have a high risk for complications and mortality.
format	article
author	Julia García Mancebo Sara de la Mata Navazo Estíbaliz López-Herce Arteta Rosario Montero Mateo Isabel María López Esteban Adriana Mazzuchelli Domínguez María Sánchez Doutel Jesús López-Herce Cid Rafael González Cortés
author_facet	Julia García Mancebo Sara de la Mata Navazo Estíbaliz López-Herce Arteta Rosario Montero Mateo Isabel María López Esteban Adriana Mazzuchelli Domínguez María Sánchez Doutel Jesús López-Herce Cid Rafael González Cortés
author_sort	Julia García Mancebo
title	A comparative two-cohort study of pediatric patients with long term stay in ICUs
title_short	A comparative two-cohort study of pediatric patients with long term stay in ICUs
title_full	A comparative two-cohort study of pediatric patients with long term stay in ICUs
title_fullStr	A comparative two-cohort study of pediatric patients with long term stay in ICUs
title_full_unstemmed	A comparative two-cohort study of pediatric patients with long term stay in ICUs
title_sort	comparative two-cohort study of pediatric patients with long term stay in icus
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6711fcda15bb45f1924485ba06cd6d98
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A comparative two-cohort study of pediatric patients with long term stay in ICUs

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