Establishing long-term efficacy in chronic disease: use of recursive partitioning and propensity score adjustment to estimate outcome in MS.
<h4>Context</h4>Establishing the long-term benefit of therapy in chronic diseases has been challenging. Long-term studies require non-randomized designs and, thus, are often confounded by biases. For example, although disease-modifying therapy in MS has a convincing benefit on several sh...
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Main Authors: | Douglas S Goodin, Jason Jones, David Li, Anthony Traboulsee, Anthony T Reder, Karola Beckmann, Andreas Konieczny, Volker Knappertz, 16-Year Long-Term Follow-up Study Investigators |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/6716c7c5b20943f18ef7c85912b553ed |
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