Light-driven decarboxylative deuteration enabled by a divergently engineered photodecarboxylase

The chemical processes for the selective incorporation of deuterium into small molecules, of interest to organic and medicinal chemistry, are well established, while the enzymatic methods remain underdeveloped. Here, the authors use an enzymatic approach employing Chlorella variabilis NC64A photodec...

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Auteurs principaux: Jian Xu, Jiajie Fan, Yujiao Lou, Weihua Xu, Zhiguo Wang, Danyang Li, Haonan Zhou, Xianfu Lin, Qi Wu
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/671c1dc0e8124a00b5cc1aca053d9f9f
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