Liposomal lipopolysaccharide initiates TRIF-dependent signaling pathway independent of CD14.
Lipopolysaccharide (LPS) is recognized by CD14 with Toll-like receptor 4 (TLR4), and initiates 2 major pathways of TLR4 signaling, the MyD88-dependent and TRIF-dependent signaling pathways. The MyD88-dependent pathway induces inflammatory responses such as the production of TNF-α, IL-6, and IL-12 vi...
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Autores principales: | Sachiko Watanabe, Yoshio Kumazawa, Joe Inoue |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/6721fa6ac81842ce943a8f7ef884b4d7 |
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