Recruitment of Cln3 cyclin to promoters controls cell cycle entry via histone deacetylase and other targets.

In yeast, the G1 cyclin Cln3 promotes cell cycle entry by activating the transcription factor SBF. In mammals, there is a parallel system for cell cycle entry in which cyclin dependent kinase (CDK) activates transcription factor E2F/Dp. Here we show that Cln3 regulates SBF by at least two different...

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Autores principales: Hongyin Wang, Lucas B Carey, Ying Cai, Herman Wijnen, Bruce Futcher
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/672c3d4978ac449fa0bea45244344a32
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