A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism
Serotonin is a potent stimulator of fat loss and energy expenditure in several species, includingC. elegans. Here, Palamiuc et al. identify the neuropeptide, FP-7, and its receptor in the intestine, NRP-22 as mediators of serotonergic body fat loss in worms.
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Nature Portfolio
2017
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oai:doaj.org-article:6730459c83d44b3b82d15e60b1cc46772021-12-02T14:42:03ZA tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism10.1038/ncomms142372041-1723https://doaj.org/article/6730459c83d44b3b82d15e60b1cc46772017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14237https://doaj.org/toc/2041-1723Serotonin is a potent stimulator of fat loss and energy expenditure in several species, includingC. elegans. Here, Palamiuc et al. identify the neuropeptide, FP-7, and its receptor in the intestine, NRP-22 as mediators of serotonergic body fat loss in worms.Lavinia PalamiucTallie NobleEmily WithamHarkaranveer RatanpalMegan VaughanSupriya SrinivasanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017) |
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Science Q Lavinia Palamiuc Tallie Noble Emily Witham Harkaranveer Ratanpal Megan Vaughan Supriya Srinivasan A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism |
description |
Serotonin is a potent stimulator of fat loss and energy expenditure in several species, includingC. elegans. Here, Palamiuc et al. identify the neuropeptide, FP-7, and its receptor in the intestine, NRP-22 as mediators of serotonergic body fat loss in worms. |
format |
article |
author |
Lavinia Palamiuc Tallie Noble Emily Witham Harkaranveer Ratanpal Megan Vaughan Supriya Srinivasan |
author_facet |
Lavinia Palamiuc Tallie Noble Emily Witham Harkaranveer Ratanpal Megan Vaughan Supriya Srinivasan |
author_sort |
Lavinia Palamiuc |
title |
A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism |
title_short |
A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism |
title_full |
A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism |
title_fullStr |
A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism |
title_full_unstemmed |
A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism |
title_sort |
tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/6730459c83d44b3b82d15e60b1cc4677 |
work_keys_str_mv |
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