A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism

Serotonin is a potent stimulator of fat loss and energy expenditure in several species, includingC. elegans. Here, Palamiuc et al. identify the neuropeptide, FP-7, and its receptor in the intestine, NRP-22 as mediators of serotonergic body fat loss in worms.

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Autores principales: Lavinia Palamiuc, Tallie Noble, Emily Witham, Harkaranveer Ratanpal, Megan Vaughan, Supriya Srinivasan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/6730459c83d44b3b82d15e60b1cc4677
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spelling oai:doaj.org-article:6730459c83d44b3b82d15e60b1cc46772021-12-02T14:42:03ZA tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism10.1038/ncomms142372041-1723https://doaj.org/article/6730459c83d44b3b82d15e60b1cc46772017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms14237https://doaj.org/toc/2041-1723Serotonin is a potent stimulator of fat loss and energy expenditure in several species, includingC. elegans. Here, Palamiuc et al. identify the neuropeptide, FP-7, and its receptor in the intestine, NRP-22 as mediators of serotonergic body fat loss in worms.Lavinia PalamiucTallie NobleEmily WithamHarkaranveer RatanpalMegan VaughanSupriya SrinivasanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Lavinia Palamiuc
Tallie Noble
Emily Witham
Harkaranveer Ratanpal
Megan Vaughan
Supriya Srinivasan
A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism
description Serotonin is a potent stimulator of fat loss and energy expenditure in several species, includingC. elegans. Here, Palamiuc et al. identify the neuropeptide, FP-7, and its receptor in the intestine, NRP-22 as mediators of serotonergic body fat loss in worms.
format article
author Lavinia Palamiuc
Tallie Noble
Emily Witham
Harkaranveer Ratanpal
Megan Vaughan
Supriya Srinivasan
author_facet Lavinia Palamiuc
Tallie Noble
Emily Witham
Harkaranveer Ratanpal
Megan Vaughan
Supriya Srinivasan
author_sort Lavinia Palamiuc
title A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism
title_short A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism
title_full A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism
title_fullStr A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism
title_full_unstemmed A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism
title_sort tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/6730459c83d44b3b82d15e60b1cc4677
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