Inhibition of Coronavirus Entry <italic toggle="yes">In Vitro</italic> and <italic toggle="yes">Ex Vivo</italic> by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain

Inhibition of Coronavirus Entry <italic toggle="yes">In Vitro</italic> and <italic toggle="yes">Ex Vivo</italic> by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain

ABSTRACT The emergence of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), the etiological agent of the 2019 coronavirus disease (COVID-19), has erupted into a global pandemic that has led to tens of millions of infections and hundreds of thousands of deaths worldwide. The developm...

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Autores principales: Victor K. Outlaw, Francesca T. Bovier, Megan C. Mears, Maria N. Cajimat, Yun Zhu, Michelle J. Lin, Amin Addetia, Nicole A. P. Lieberman, Vikas Peddu, Xuping Xie, Pei-Yong Shi, Alexander L. Greninger, Samuel H. Gellman, Dennis A. Bente, Anne Moscona, Matteo Porotto
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
SARS-CoV-2
spike protein
fusion inhibitor
lipopeptide
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/67347a10ef8144ada066a6a8fb7f2582
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https://doaj.org/article/67347a10ef8144ada066a6a8fb7f2582

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