Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity

Hepatokines are proteins secreted by the liver that can regulate whole body metabolism. Here the authors identify apolipoprotein J as a hepatokine that regulates muscle glucose metabolism and insulin resistance through a low-density lipoprotein receptor-related protein−2 mediated mechanism in mice....

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Autores principales:	Ji A Seo, Min-Cheol Kang, Won-Mo Yang, Won Min Hwang, Sang Soo Kim, Soo Hyun Hong, Jee-In Heo, Achana Vijyakumar, Leandro Pereira de Moura, Aykut Uner, Hu Huang, Seung Hwan Lee, Inês S. Lima, Kyong Soo Park, Min Seon Kim, Yossi Dagon, Thomas E. Willnow, Vanita Aroda, Theodore P. Ciaraldi, Robert R. Henry, Young-Bum Kim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6735e33c49584e2dadb77deb37175325
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spelling	oai:doaj.org-article:6735e33c49584e2dadb77deb371753252021-12-02T14:41:24ZApolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity10.1038/s41467-020-15963-w2041-1723https://doaj.org/article/6735e33c49584e2dadb77deb371753252020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15963-whttps://doaj.org/toc/2041-1723Hepatokines are proteins secreted by the liver that can regulate whole body metabolism. Here the authors identify apolipoprotein J as a hepatokine that regulates muscle glucose metabolism and insulin resistance through a low-density lipoprotein receptor-related protein−2 mediated mechanism in mice.Ji A SeoMin-Cheol KangWon-Mo YangWon Min HwangSang Soo KimSoo Hyun HongJee-In HeoAchana VijyakumarLeandro Pereira de MouraAykut UnerHu HuangSeung Hwan LeeInês S. LimaKyong Soo ParkMin Seon KimYossi DagonThomas E. WillnowVanita ArodaTheodore P. CiaraldiRobert R. HenryYoung-Bum KimNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ji A Seo Min-Cheol Kang Won-Mo Yang Won Min Hwang Sang Soo Kim Soo Hyun Hong Jee-In Heo Achana Vijyakumar Leandro Pereira de Moura Aykut Uner Hu Huang Seung Hwan Lee Inês S. Lima Kyong Soo Park Min Seon Kim Yossi Dagon Thomas E. Willnow Vanita Aroda Theodore P. Ciaraldi Robert R. Henry Young-Bum Kim Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
description	Hepatokines are proteins secreted by the liver that can regulate whole body metabolism. Here the authors identify apolipoprotein J as a hepatokine that regulates muscle glucose metabolism and insulin resistance through a low-density lipoprotein receptor-related protein−2 mediated mechanism in mice.
format	article
author	Ji A Seo Min-Cheol Kang Won-Mo Yang Won Min Hwang Sang Soo Kim Soo Hyun Hong Jee-In Heo Achana Vijyakumar Leandro Pereira de Moura Aykut Uner Hu Huang Seung Hwan Lee Inês S. Lima Kyong Soo Park Min Seon Kim Yossi Dagon Thomas E. Willnow Vanita Aroda Theodore P. Ciaraldi Robert R. Henry Young-Bum Kim
author_facet	Ji A Seo Min-Cheol Kang Won-Mo Yang Won Min Hwang Sang Soo Kim Soo Hyun Hong Jee-In Heo Achana Vijyakumar Leandro Pereira de Moura Aykut Uner Hu Huang Seung Hwan Lee Inês S. Lima Kyong Soo Park Min Seon Kim Yossi Dagon Thomas E. Willnow Vanita Aroda Theodore P. Ciaraldi Robert R. Henry Young-Bum Kim
author_sort	Ji A Seo
title	Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
title_short	Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
title_full	Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
title_fullStr	Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
title_full_unstemmed	Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
title_sort	apolipoprotein j is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6735e33c49584e2dadb77deb37175325
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Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity

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