Mutation bias and GC content shape antimutator invasions

Mutators are expected to re-evolve low mutation rates to reduce deleterious load, but empirical evidence is mixed. Here, the authors show that load can vary across mutators and genetic backgrounds, which their simulations suggest can substantially alter antimutator dynamics.

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Auteurs principaux: Alejandro Couce, Olivier Tenaillon
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
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Accès en ligne:https://doaj.org/article/67417fa7d81b4f77964910427aefd29a
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