Serum trace elements in insulin-dependent and non-insulin-dependent diabetes: a comparative study

Ahmed M Ahmed,1 Omar F Khabour,1,2 Akram H Awadalla,3 Hisham A Waggiallah4 1Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Taibah University, Medina, Saudi Arabia; 2Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of...

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Autores principales:	Ahmed AM, Khabour OF, Awadalla AH, Waggiallah HA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Trace elements diabetes mellitus IDDM NIDDM. Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/67493d7e6a6b4200b75d75d68dfddb9e
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spelling	oai:doaj.org-article:67493d7e6a6b4200b75d75d68dfddb9e2021-12-02T08:36:31ZSerum trace elements in insulin-dependent and non-insulin-dependent diabetes: a comparative study1178-7007https://doaj.org/article/67493d7e6a6b4200b75d75d68dfddb9e2018-12-01T00:00:00Zhttps://www.dovepress.com/serum-trace-elements-in-insulin-dependent-and-non-insulin-dependent-di-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Ahmed M Ahmed,1 Omar F Khabour,1,2 Akram H Awadalla,3 Hisham A Waggiallah4 1Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Taibah University, Medina, Saudi Arabia; 2Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan; 3Department of Clinical Chemistry, College of Medical Laboratory Sciences, Kordofan University, Alobayid, Sudan; 4Department of Medical Laboratory Sciences, Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia Background: Diabetes mellitus is associated with imbalance in body trace elements. The aim of the current investigation was to compare the levels of trace elements (Zn, Mg, Mn, Cu, Na, K, Fe, Ca, Cr, and Se) in insulin dependent (IDDM) and non-insulin dependent (NIDDM) diabetes. Methods: A total of 100 patients with diabetes (40 IDDM and 60 NIDDM) and 50 healthy subjects were recruited in the study from both genders. Biochemical measures include glucose, lipids, and HbA1C. Results: The results showed that Zn, Mg, Cu and Cr were significant lower in patients with diabetes compared to the control group (P<0.01). In addition, Zn and Cr were significantly lower in IDDM than NIDDM (P<0.05). Moreover, Zn and Mg levels were inversely correlated with HbA1c in IDDM and NIDDM (P<0.05). Zn was inversely correlated with fasting blood glucose in IDDM (P<0.05). Finally, no correlation between trace element levels with BMI was found (P>0.05). Conclusion: Disturbance in trace element profile among IDDM and NIDDM is similar. Keywords: trace elements, diabetes mellitus, IDDM, NIDDMAhmed AMKhabour OFAwadalla AHWaggiallah HADove Medical PressarticleTrace elementsdiabetes mellitusIDDMNIDDM.Specialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 11, Pp 887-892 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Trace elements diabetes mellitus IDDM NIDDM. Specialties of internal medicine RC581-951
spellingShingle	Trace elements diabetes mellitus IDDM NIDDM. Specialties of internal medicine RC581-951 Ahmed AM Khabour OF Awadalla AH Waggiallah HA Serum trace elements in insulin-dependent and non-insulin-dependent diabetes: a comparative study
description	Ahmed M Ahmed,1 Omar F Khabour,1,2 Akram H Awadalla,3 Hisham A Waggiallah4 1Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Taibah University, Medina, Saudi Arabia; 2Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan; 3Department of Clinical Chemistry, College of Medical Laboratory Sciences, Kordofan University, Alobayid, Sudan; 4Department of Medical Laboratory Sciences, Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia Background: Diabetes mellitus is associated with imbalance in body trace elements. The aim of the current investigation was to compare the levels of trace elements (Zn, Mg, Mn, Cu, Na, K, Fe, Ca, Cr, and Se) in insulin dependent (IDDM) and non-insulin dependent (NIDDM) diabetes. Methods: A total of 100 patients with diabetes (40 IDDM and 60 NIDDM) and 50 healthy subjects were recruited in the study from both genders. Biochemical measures include glucose, lipids, and HbA1C. Results: The results showed that Zn, Mg, Cu and Cr were significant lower in patients with diabetes compared to the control group (P<0.01). In addition, Zn and Cr were significantly lower in IDDM than NIDDM (P<0.05). Moreover, Zn and Mg levels were inversely correlated with HbA1c in IDDM and NIDDM (P<0.05). Zn was inversely correlated with fasting blood glucose in IDDM (P<0.05). Finally, no correlation between trace element levels with BMI was found (P>0.05). Conclusion: Disturbance in trace element profile among IDDM and NIDDM is similar. Keywords: trace elements, diabetes mellitus, IDDM, NIDDM
format	article
author	Ahmed AM Khabour OF Awadalla AH Waggiallah HA
author_facet	Ahmed AM Khabour OF Awadalla AH Waggiallah HA
author_sort	Ahmed AM
title	Serum trace elements in insulin-dependent and non-insulin-dependent diabetes: a comparative study
title_short	Serum trace elements in insulin-dependent and non-insulin-dependent diabetes: a comparative study
title_full	Serum trace elements in insulin-dependent and non-insulin-dependent diabetes: a comparative study
title_fullStr	Serum trace elements in insulin-dependent and non-insulin-dependent diabetes: a comparative study
title_full_unstemmed	Serum trace elements in insulin-dependent and non-insulin-dependent diabetes: a comparative study
title_sort	serum trace elements in insulin-dependent and non-insulin-dependent diabetes: a comparative study
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/67493d7e6a6b4200b75d75d68dfddb9e
work_keys_str_mv	AT ahmedam serumtraceelementsininsulindependentandnoninsulindependentdiabetesacomparativestudy AT khabourof serumtraceelementsininsulindependentandnoninsulindependentdiabetesacomparativestudy AT awadallaah serumtraceelementsininsulindependentandnoninsulindependentdiabetesacomparativestudy AT waggiallahha serumtraceelementsininsulindependentandnoninsulindependentdiabetesacomparativestudy
_version_	1718398451586170880

Serum trace elements in insulin-dependent and non-insulin-dependent diabetes: a comparative study

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