Targeting myeloid cells to the brain using non-myeloablative conditioning.
Bone marrow-derived cells (BMDCs) are able to colonize the central nervous system (CNS) at sites of damage. This ability makes BMDCs an ideal cellular vehicle for transferring therapeutic genes/molecules to the CNS. However, conditioning is required for bone marrow-derived myeloid cells to engraft i...
Guardado en:
Autores principales: | Chotima Böttcher, Francisco Fernández-Klett, Nadine Gladow, Simone Rolfes, Josef Priller |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/67571b8b4dea43199c3a189ebe3841b5 |
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