Human Cancer Cells Signal Their Competitive Fitness Through MYC Activity

Human Cancer Cells Signal Their Competitive Fitness Through MYC Activity

Abstract MYC-mediated cell competition is a cell-cell interaction mechanism known to play an evolutionary role during development from Drosophila to mammals. Cells expressing low levels of MYC, called losers, are committed to die by nearby cells with high MYC activity, called winners, that overproli...

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Autores principales: Simone Di Giacomo, Manuela Sollazzo, Dario de Biase, Moira Ragazzi, Paola Bellosta, Annalisa Pession, Daniela Grifoni
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/67689ddb725f42bc924694dd326ec759
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