SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems

SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems

Infection with SARS-CoV-2 triggers the simultaneous activation of innate inflammatory pathways including the complement system and the kallikrein-kinin system (KKS) generating in the process potent vasoactive peptides that contribute to severe acute respiratory syndrome (SARS) and multi-organ failur...

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Bibliographic Details
Main Authors: Anne G. Savitt, Samantha Manimala, Tiara White, Marina Fandaros, Wei Yin, Huiquan Duan, Xin Xu, Brian V. Geisbrecht, David A. Rubenstein, Allen P. Kaplan, Ellinor I. Peerschke, Berhane Ghebrehiwet
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
Sars-CoV-2
complement
bradykinin
COVID-19
kinin-kallikrein system
post COVID “long-haulers”
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/6770e2f74e8948b8a62d2b8fa28fe7c4
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https://doaj.org/article/6770e2f74e8948b8a62d2b8fa28fe7c4

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