Doxycycline in the Coronavirus Disease 2019 Therapy

Karolina Dorobisz,1 Tadeusz Dorobisz,2 Dariusz Janczak,2 Tomasz Zatoński1 1Department of Otolaryngology, Head and Neck Surgery, Wroclaw Medical University, Wroclaw, Poland; 2Department of Vascular Surgery, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Karolina Dorobisz Email...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Dorobisz K, Dorobisz T, Janczak D, Zatoński T
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2021
Materias:
Acceso en línea:https://doaj.org/article/67750291f4de4589a94402750e56b5e8
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:67750291f4de4589a94402750e56b5e8
record_format dspace
spelling oai:doaj.org-article:67750291f4de4589a94402750e56b5e82021-12-02T17:25:47ZDoxycycline in the Coronavirus Disease 2019 Therapy1178-203Xhttps://doaj.org/article/67750291f4de4589a94402750e56b5e82021-09-01T00:00:00Zhttps://www.dovepress.com/doxycycline-in-the-coronavirus-disease-2019-therapy-peer-reviewed-fulltext-article-TCRMhttps://doaj.org/toc/1178-203XKarolina Dorobisz,1 Tadeusz Dorobisz,2 Dariusz Janczak,2 Tomasz Zatoński1 1Department of Otolaryngology, Head and Neck Surgery, Wroclaw Medical University, Wroclaw, Poland; 2Department of Vascular Surgery, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Karolina Dorobisz Email dorobiszkarolina@gmail.comAbstract: Acute respiratory syndrome, associated with coronavirus 2 (SARS-CoV-2), is the most important medical and epidemic problem of today. The biggest challenge is to find an effective treatment and to reduce the need for hospitalisation. In the article, the patients with mild to moderate coronavirus disease 2019 (COVID-19) treated with doxycycline with significant improvement have been discussed. Doxycycline is a known antibiotic, but also an anti-inflammatory and immunomodulatory drug, so it seems to be ideal for the treatment of COVID-19. Doxycycline, as an easily available and low-cost medication, should be considered as a COVID-19 therapy in all patients in the first days of the symptoms of a SARS-CoV-2 infection. Due to its immunomodulatory, anti-inflammatory, cardioprotective and antiviral effects, it seems to be an ideal drug for patients with mild, moderate and severe disease. A large multicentre study is needed to evaluate the effects of this medication.Keywords: COVID-19, COVID-19 therapy, doxycycline, SARS-CoV-2Dorobisz KDorobisz TJanczak DZatoński TDove Medical Pressarticlecovid-19covid-19 therapydoxycyclinesars-cov-2Therapeutics. PharmacologyRM1-950ENTherapeutics and Clinical Risk Management, Vol Volume 17, Pp 1023-1026 (2021)
institution DOAJ
collection DOAJ
language EN
topic covid-19
covid-19 therapy
doxycycline
sars-cov-2
Therapeutics. Pharmacology
RM1-950
spellingShingle covid-19
covid-19 therapy
doxycycline
sars-cov-2
Therapeutics. Pharmacology
RM1-950
Dorobisz K
Dorobisz T
Janczak D
Zatoński T
Doxycycline in the Coronavirus Disease 2019 Therapy
description Karolina Dorobisz,1 Tadeusz Dorobisz,2 Dariusz Janczak,2 Tomasz Zatoński1 1Department of Otolaryngology, Head and Neck Surgery, Wroclaw Medical University, Wroclaw, Poland; 2Department of Vascular Surgery, Wroclaw Medical University, Wroclaw, PolandCorrespondence: Karolina Dorobisz Email dorobiszkarolina@gmail.comAbstract: Acute respiratory syndrome, associated with coronavirus 2 (SARS-CoV-2), is the most important medical and epidemic problem of today. The biggest challenge is to find an effective treatment and to reduce the need for hospitalisation. In the article, the patients with mild to moderate coronavirus disease 2019 (COVID-19) treated with doxycycline with significant improvement have been discussed. Doxycycline is a known antibiotic, but also an anti-inflammatory and immunomodulatory drug, so it seems to be ideal for the treatment of COVID-19. Doxycycline, as an easily available and low-cost medication, should be considered as a COVID-19 therapy in all patients in the first days of the symptoms of a SARS-CoV-2 infection. Due to its immunomodulatory, anti-inflammatory, cardioprotective and antiviral effects, it seems to be an ideal drug for patients with mild, moderate and severe disease. A large multicentre study is needed to evaluate the effects of this medication.Keywords: COVID-19, COVID-19 therapy, doxycycline, SARS-CoV-2
format article
author Dorobisz K
Dorobisz T
Janczak D
Zatoński T
author_facet Dorobisz K
Dorobisz T
Janczak D
Zatoński T
author_sort Dorobisz K
title Doxycycline in the Coronavirus Disease 2019 Therapy
title_short Doxycycline in the Coronavirus Disease 2019 Therapy
title_full Doxycycline in the Coronavirus Disease 2019 Therapy
title_fullStr Doxycycline in the Coronavirus Disease 2019 Therapy
title_full_unstemmed Doxycycline in the Coronavirus Disease 2019 Therapy
title_sort doxycycline in the coronavirus disease 2019 therapy
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/67750291f4de4589a94402750e56b5e8
work_keys_str_mv AT dorobiszk doxycyclineinthecoronavirusdisease2019therapy
AT dorobiszt doxycyclineinthecoronavirusdisease2019therapy
AT janczakd doxycyclineinthecoronavirusdisease2019therapy
AT zatonskit doxycyclineinthecoronavirusdisease2019therapy
_version_ 1718380913583194112