RESEARCH OF THERAPEUTIC ALTERNATIVES FOR SNAKEBITE IN AGROINDUSTRY RESIDUES OF TROPICAL FRUITS

This paper tries to demonstrate that agroindustrial residues, such as Vitis vinifera and Citrus sinensis seeds and the Mangifera indica Kernel, have the capacity of neutralize some of the enzymatic effects induced by Bothrops asper and Porthidium nasutum venoms, in addition to the inhibitory abilit...

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Autores principales:	Jaime A. PEREAÑEZ, Arley C. PATIÑO, Gelmy CIRO, Leidy J. VARGAS, Julieta VÁSQUEZ, Andrea SALAZAR, Jessica P. REY
Formato:	article
Lenguaje:	EN
Publicado:	Universidad de Antioquia 2009
Materias:	Bothrops asper Porthidium nasutum Mangifera indica Vitis vinifera Citrus sinensis tannins. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
Acceso en línea:	https://doaj.org/article/6790781cf54a4d57a045bc9989f96469
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spelling	oai:doaj.org-article:6790781cf54a4d57a045bc9989f964692021-11-19T04:14:50ZRESEARCH OF THERAPEUTIC ALTERNATIVES FOR SNAKEBITE IN AGROINDUSTRY RESIDUES OF TROPICAL FRUITS0121-40042145-2660https://doaj.org/article/6790781cf54a4d57a045bc9989f964692009-11-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/3019https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660 This paper tries to demonstrate that agroindustrial residues, such as Vitis vinifera and Citrus sinensis seeds and the Mangifera indica Kernel, have the capacity of neutralize some of the enzymatic effects induced by Bothrops asper and Porthidium nasutum venoms, in addition to the inhibitory ability of some microorganism growth of the normal flora of the serpent fangs and mouth. That is the extracts of M. indica and Vitis vinifera have a good inhibitory ability of the phospholipase A2 activity in a dose dependent manner and if they have a major neutralizing potency against the P. nasutum venom activity. Against the proteolytic effect induced by both snakes venom, V. vinifera shows the best inhibition percentages in a dependent way of the amount of extract used. Against the coagulant activity of B. asper venom, the species M. indica and V. vinifera are able to prolong the coagulation time up ~ 31 and 13 times, respectively, to the corresponding positive control time. M. indica and V. vinifera inhibit the growth of Escherichia coli and Staphylococcus aureus. On the other hand, the etanolic extract of C. sinensis seeds does not show promising inhibition results. Jaime A. PEREAÑEZArley C. PATIÑOGelmy CIROLeidy J. VARGASJulieta VÁSQUEZAndrea SALAZARJessica P. REYUniversidad de AntioquiaarticleBothrops asperPorthidium nasutumMangifera indicaVitis viniferaCitrus sinensistannins.Food processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 16, Iss 3 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Bothrops asper Porthidium nasutum Mangifera indica Vitis vinifera Citrus sinensis tannins. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
spellingShingle	Bothrops asper Porthidium nasutum Mangifera indica Vitis vinifera Citrus sinensis tannins. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 Jaime A. PEREAÑEZ Arley C. PATIÑO Gelmy CIRO Leidy J. VARGAS Julieta VÁSQUEZ Andrea SALAZAR Jessica P. REY RESEARCH OF THERAPEUTIC ALTERNATIVES FOR SNAKEBITE IN AGROINDUSTRY RESIDUES OF TROPICAL FRUITS
description	This paper tries to demonstrate that agroindustrial residues, such as Vitis vinifera and Citrus sinensis seeds and the Mangifera indica Kernel, have the capacity of neutralize some of the enzymatic effects induced by Bothrops asper and Porthidium nasutum venoms, in addition to the inhibitory ability of some microorganism growth of the normal flora of the serpent fangs and mouth. That is the extracts of M. indica and Vitis vinifera have a good inhibitory ability of the phospholipase A2 activity in a dose dependent manner and if they have a major neutralizing potency against the P. nasutum venom activity. Against the proteolytic effect induced by both snakes venom, V. vinifera shows the best inhibition percentages in a dependent way of the amount of extract used. Against the coagulant activity of B. asper venom, the species M. indica and V. vinifera are able to prolong the coagulation time up ~ 31 and 13 times, respectively, to the corresponding positive control time. M. indica and V. vinifera inhibit the growth of Escherichia coli and Staphylococcus aureus. On the other hand, the etanolic extract of C. sinensis seeds does not show promising inhibition results.
format	article
author	Jaime A. PEREAÑEZ Arley C. PATIÑO Gelmy CIRO Leidy J. VARGAS Julieta VÁSQUEZ Andrea SALAZAR Jessica P. REY
author_facet	Jaime A. PEREAÑEZ Arley C. PATIÑO Gelmy CIRO Leidy J. VARGAS Julieta VÁSQUEZ Andrea SALAZAR Jessica P. REY
author_sort	Jaime A. PEREAÑEZ
title	RESEARCH OF THERAPEUTIC ALTERNATIVES FOR SNAKEBITE IN AGROINDUSTRY RESIDUES OF TROPICAL FRUITS
title_short	RESEARCH OF THERAPEUTIC ALTERNATIVES FOR SNAKEBITE IN AGROINDUSTRY RESIDUES OF TROPICAL FRUITS
title_full	RESEARCH OF THERAPEUTIC ALTERNATIVES FOR SNAKEBITE IN AGROINDUSTRY RESIDUES OF TROPICAL FRUITS
title_fullStr	RESEARCH OF THERAPEUTIC ALTERNATIVES FOR SNAKEBITE IN AGROINDUSTRY RESIDUES OF TROPICAL FRUITS
title_full_unstemmed	RESEARCH OF THERAPEUTIC ALTERNATIVES FOR SNAKEBITE IN AGROINDUSTRY RESIDUES OF TROPICAL FRUITS
title_sort	research of therapeutic alternatives for snakebite in agroindustry residues of tropical fruits
publisher	Universidad de Antioquia
publishDate	2009
url	https://doaj.org/article/6790781cf54a4d57a045bc9989f96469
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RESEARCH OF THERAPEUTIC ALTERNATIVES FOR SNAKEBITE IN AGROINDUSTRY RESIDUES OF TROPICAL FRUITS

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