IL-17-producing γδ T cells enhance bone regeneration

IL-17-producing γδ T cells enhance bone regeneration

γδ T cells are innate-like lymphocytes that regulate immune responses by producing IL-17A or IFN-γ, but have no known role in bone healing. Here the authors show a nonimmune bone-regenerative function of IL-17A produced by the Vγ6+ subset in mice.

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Autores principales: Takehito Ono, Kazuo Okamoto, Tomoki Nakashima, Takeshi Nitta, Shohei Hori, Yoichiro Iwakura, Hiroshi Takayanagi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/679616e474a54998a71bde011fcf764b
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spelling oai:doaj.org-article:679616e474a54998a71bde011fcf764b2021-12-02T16:57:05ZIL-17-producing γδ T cells enhance bone regeneration10.1038/ncomms109282041-1723https://doaj.org/article/679616e474a54998a71bde011fcf764b2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10928https://doaj.org/toc/2041-1723γδ T cells are innate-like lymphocytes that regulate immune responses by producing IL-17A or IFN-γ, but have no known role in bone healing. Here the authors show a nonimmune bone-regenerative function of IL-17A produced by the Vγ6+ subset in mice.Takehito OnoKazuo OkamotoTomoki NakashimaTakeshi NittaShohei HoriYoichiro IwakuraHiroshi TakayanagiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Takehito Ono
Kazuo Okamoto
Tomoki Nakashima
Takeshi Nitta
Shohei Hori
Yoichiro Iwakura
Hiroshi Takayanagi
IL-17-producing γδ T cells enhance bone regeneration
description γδ T cells are innate-like lymphocytes that regulate immune responses by producing IL-17A or IFN-γ, but have no known role in bone healing. Here the authors show a nonimmune bone-regenerative function of IL-17A produced by the Vγ6+ subset in mice.
format article
author Takehito Ono
Kazuo Okamoto
Tomoki Nakashima
Takeshi Nitta
Shohei Hori
Yoichiro Iwakura
Hiroshi Takayanagi
author_facet Takehito Ono
Kazuo Okamoto
Tomoki Nakashima
Takeshi Nitta
Shohei Hori
Yoichiro Iwakura
Hiroshi Takayanagi
author_sort Takehito Ono
title IL-17-producing γδ T cells enhance bone regeneration
title_short IL-17-producing γδ T cells enhance bone regeneration
title_full IL-17-producing γδ T cells enhance bone regeneration
title_fullStr IL-17-producing γδ T cells enhance bone regeneration
title_full_unstemmed IL-17-producing γδ T cells enhance bone regeneration
title_sort il-17-producing γδ t cells enhance bone regeneration
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/679616e474a54998a71bde011fcf764b
work_keys_str_mv AT takehitoono il17producinggdtcellsenhanceboneregeneration
AT kazuookamoto il17producinggdtcellsenhanceboneregeneration
AT tomokinakashima il17producinggdtcellsenhanceboneregeneration
AT takeshinitta il17producinggdtcellsenhanceboneregeneration
AT shoheihori il17producinggdtcellsenhanceboneregeneration
AT yoichiroiwakura il17producinggdtcellsenhanceboneregeneration
AT hiroshitakayanagi il17producinggdtcellsenhanceboneregeneration
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