Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage
Debugging a genetic circuit is frustrated by the inability to characterize parts in the context of the circuit. Here the authors use RNA-seq and ribosome profiling to take ‘snapshots’ of a large circuit in different states.
Guardado en:
Autores principales: | , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/67a63b86a841423c9a18630376a49a5c |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:67a63b86a841423c9a18630376a49a5c |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:67a63b86a841423c9a18630376a49a5c2021-12-02T18:07:54ZGenetic circuit characterization by inferring RNA polymerase movement and ribosome usage10.1038/s41467-020-18630-22041-1723https://doaj.org/article/67a63b86a841423c9a18630376a49a5c2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18630-2https://doaj.org/toc/2041-1723Debugging a genetic circuit is frustrated by the inability to characterize parts in the context of the circuit. Here the authors use RNA-seq and ribosome profiling to take ‘snapshots’ of a large circuit in different states.Amin Espah BorujeniJing ZhangHamid DoosthosseiniAlec A. K. NielsenChristopher A. VoigtNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Amin Espah Borujeni Jing Zhang Hamid Doosthosseini Alec A. K. Nielsen Christopher A. Voigt Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage |
description |
Debugging a genetic circuit is frustrated by the inability to characterize parts in the context of the circuit. Here the authors use RNA-seq and ribosome profiling to take ‘snapshots’ of a large circuit in different states. |
format |
article |
author |
Amin Espah Borujeni Jing Zhang Hamid Doosthosseini Alec A. K. Nielsen Christopher A. Voigt |
author_facet |
Amin Espah Borujeni Jing Zhang Hamid Doosthosseini Alec A. K. Nielsen Christopher A. Voigt |
author_sort |
Amin Espah Borujeni |
title |
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage |
title_short |
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage |
title_full |
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage |
title_fullStr |
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage |
title_full_unstemmed |
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage |
title_sort |
genetic circuit characterization by inferring rna polymerase movement and ribosome usage |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/67a63b86a841423c9a18630376a49a5c |
work_keys_str_mv |
AT aminespahborujeni geneticcircuitcharacterizationbyinferringrnapolymerasemovementandribosomeusage AT jingzhang geneticcircuitcharacterizationbyinferringrnapolymerasemovementandribosomeusage AT hamiddoosthosseini geneticcircuitcharacterizationbyinferringrnapolymerasemovementandribosomeusage AT alecaknielsen geneticcircuitcharacterizationbyinferringrnapolymerasemovementandribosomeusage AT christopheravoigt geneticcircuitcharacterizationbyinferringrnapolymerasemovementandribosomeusage |
_version_ |
1718378633192538112 |