In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis.
The mammalian Interferon induced transmembrane protein 1 (Ifitm1) gene was originally identified as a member of a gene family highly inducible by type I and type II interferons. Based on expression analyses, it was suggested to be required for normal primordial germ cell migration. The knockdown of...
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Auteurs principaux: | Ingeborg Klymiuk, Lukas Kenner, Thure Adler, Dirk H Busch, Auke Boersma, Martin Irmler, Barbara Fridrich, Valérie Gailus-Durner, Helmut Fuchs, Nicole Leitner, Mathias Müller, Ralf Kühn, Michaela Schlederer, Irina Treise, Martin Hrabě de Angelis, Johannes Beckers |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
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Accès en ligne: | https://doaj.org/article/67a8b1d5bb6c43e88eebd93023247cfb |
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