Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB
Aim. To evaluate efficiency and tolerability of diabeton MB/metformin combination in patients failing to achieve optimal glycemic control when onmetformin monotherapy and prove advantages of this combination over combined low-dose therapy with glibenclamide and metformin. Materials and methods. Th...
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Endocrinology Research Centre
2009
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oai:doaj.org-article:67a94a81996746ccbe2c141ef7a7c7642021-11-14T09:00:14ZEfficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB2072-03512072-037810.14341/2072-0351-5708https://doaj.org/article/67a94a81996746ccbe2c141ef7a7c7642009-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5708https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aim. To evaluate efficiency and tolerability of diabeton MB/metformin combination in patients failing to achieve optimal glycemic control when onmetformin monotherapy and prove advantages of this combination over combined low-dose therapy with glibenclamide and metformin. Materials and methods. The study included 464 patients with type 2 diabetes mellitus who poorly responded to metformin monotherapy. It was supplementedby diabeton MB. Efficiency and tolerability of combined treatment was evaluated from dynamics of glycemia and frequency of side-effects.40 patients were included in detailed comparative assessment (laboratory and instrumental, CGMS) of this monotherapy and fixed low-dose combinationof glibenclamide with metformin. Results. Results of comparison show that diabeton MB/metformin combination ensured most optimal glycemic control with a minimal risk of side effects. Conclusion. Diabeton MB/metformin combination is convenient, efficient and safe.Alexander Sergeevich AmetovLyudmila Nikolaevna BogdanovaEndocrinology Research Centrearticletype 2 diabetes mellitusdiabeton mbglycated hemoglobincontinuous glucose monitoringNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 12, Iss 4, Pp 68-71 (2009) |
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DOAJ |
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EN RU |
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type 2 diabetes mellitus diabeton mb glycated hemoglobin continuous glucose monitoring Nutritional diseases. Deficiency diseases RC620-627 |
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type 2 diabetes mellitus diabeton mb glycated hemoglobin continuous glucose monitoring Nutritional diseases. Deficiency diseases RC620-627 Alexander Sergeevich Ametov Lyudmila Nikolaevna Bogdanova Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| description |
Aim. To evaluate efficiency and tolerability of diabeton MB/metformin combination in patients failing to achieve optimal glycemic control when onmetformin monotherapy and prove advantages of this combination over combined low-dose therapy with glibenclamide and metformin. Materials and methods. The study included 464 patients with type 2 diabetes mellitus who poorly responded to metformin monotherapy. It was supplementedby diabeton MB. Efficiency and tolerability of combined treatment was evaluated from dynamics of glycemia and frequency of side-effects.40 patients were included in detailed comparative assessment (laboratory and instrumental, CGMS) of this monotherapy and fixed low-dose combinationof glibenclamide with metformin. Results. Results of comparison show that diabeton MB/metformin combination ensured most optimal glycemic control with a minimal risk of side effects. Conclusion. Diabeton MB/metformin combination is convenient, efficient and safe. |
| format |
article |
| author |
Alexander Sergeevich Ametov Lyudmila Nikolaevna Bogdanova |
| author_facet |
Alexander Sergeevich Ametov Lyudmila Nikolaevna Bogdanova |
| author_sort |
Alexander Sergeevich Ametov |
| title |
Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| title_short |
Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| title_full |
Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| title_fullStr |
Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| title_full_unstemmed |
Efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton MB |
| title_sort |
efficiency and safety of transfer of type 2 diabetes patients inadequately controlled on metformin alone to combined therapy with metformin and diabeton mb |
| publisher |
Endocrinology Research Centre |
| publishDate |
2009 |
| url |
https://doaj.org/article/67a94a81996746ccbe2c141ef7a7c764 |
| work_keys_str_mv |
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| _version_ |
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