Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells

Cancer vaccines often fail to generate clinically relevant effects. Here, the authors generate a nanosized cytomembrane vaccine based on fusion between dendritic cells and cancer cells, and show them to activate anti-tumor immune responses via their antigen presenting and T-cell activating functions...

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Autores principales:	Wen-Long Liu, Mei-Zhen Zou, Tao Liu, Jin-Yue Zeng, Xue Li, Wu-Yang Yu, Chu-Xin Li, Jing-Jie Ye, Wen Song, Jun Feng, Xian-Zheng Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/67ae9c77ce0a4c3384f5b7c2f11709b8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:67ae9c77ce0a4c3384f5b7c2f11709b82021-12-02T17:02:10ZCytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells10.1038/s41467-019-11157-12041-1723https://doaj.org/article/67ae9c77ce0a4c3384f5b7c2f11709b82019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11157-1https://doaj.org/toc/2041-1723Cancer vaccines often fail to generate clinically relevant effects. Here, the authors generate a nanosized cytomembrane vaccine based on fusion between dendritic cells and cancer cells, and show them to activate anti-tumor immune responses via their antigen presenting and T-cell activating functions.Wen-Long LiuMei-Zhen ZouTao LiuJin-Yue ZengXue LiWu-Yang YuChu-Xin LiJing-Jie YeWen SongJun FengXian-Zheng ZhangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wen-Long Liu Mei-Zhen Zou Tao Liu Jin-Yue Zeng Xue Li Wu-Yang Yu Chu-Xin Li Jing-Jie Ye Wen Song Jun Feng Xian-Zheng Zhang Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells
description	Cancer vaccines often fail to generate clinically relevant effects. Here, the authors generate a nanosized cytomembrane vaccine based on fusion between dendritic cells and cancer cells, and show them to activate anti-tumor immune responses via their antigen presenting and T-cell activating functions.
format	article
author	Wen-Long Liu Mei-Zhen Zou Tao Liu Jin-Yue Zeng Xue Li Wu-Yang Yu Chu-Xin Li Jing-Jie Ye Wen Song Jun Feng Xian-Zheng Zhang
author_facet	Wen-Long Liu Mei-Zhen Zou Tao Liu Jin-Yue Zeng Xue Li Wu-Yang Yu Chu-Xin Li Jing-Jie Ye Wen Song Jun Feng Xian-Zheng Zhang
author_sort	Wen-Long Liu
title	Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells
title_short	Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells
title_full	Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells
title_fullStr	Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells
title_full_unstemmed	Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells
title_sort	cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/67ae9c77ce0a4c3384f5b7c2f11709b8
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Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells

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